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The document provides essential guidelines for managing cholera outbreaks. It includes instructions for preparing oral rehydration solutions (ORS) using simple ingredients like sugar and salt to treat dehydration caused by cholera. The text also emphasizes the importance of access to clean water, sa
...
nitation, and hygiene to prevent the spread of the disease. It is part of the World Health Organization's effort to provide clear, actionable steps for controlling cholera in affected areas.
more
The WHO Guide on Oral Cholera Vaccines in Mass Immunization Campaigns provides guidance on the planning and implementation of oral cholera vaccine (OCV) campaigns. It covers key aspects such as when and where to use OCVs, vaccine specifications, and recommendations for use in endemic areas, outbreak
...
settings, and complex emergencies. The document outlines steps for macro- and micro-planning, logistics, budgeting, human resource allocation, and risk communication. It also highlights challenges, including cold chain management, vaccine supply, and community engagement, ensuring that vaccination campaigns are efficient and effective in reducing cholera outbreaks.
more
The technical note by the Global Task Force on Cholera Control (GTFCC) discusses the use of Oral Cholera Vaccines (OCVs) for international workers and travelers in cholera-affected areas. It reviews the effectiveness of WHO-prequalified vaccines (Dukoral®, Shanchol™, and Euvichol®), emphasizing
...
their role in preventing infection and reducing transmission risks.
The document highlights concerns about travelers contracting cholera in endemic regions and potentially spreading the disease upon returning home. While the overall risk is considered low, certain groups, such as humanitarian workers and travelers to high-risk areas like South Asia, face a higher exposure.
Recommendations include vaccination for emergency and relief workers who may come into direct contact with cholera patients or contaminated environments. However, routine vaccination for general travelers is not widely recommended. The note also calls for better surveillance and studies to assess the potential of vaccines in preventing international transmission.
more
The Interim Guidance on Cholera Rapid Diagnostic Tests (RDTs) by the Global Task Force on Cholera Control (GTFCC) provides recommendations for using RDTs to detect cholera in areas with limited laboratory capacity. It highlights the advantages of RDTs, such as rapid detection (within 30 minutes), ea
...
se of use by non-laboratory personnel, and their role in early outbreak identification and surveillance. However, it emphasizes that RDTs should not replace culture or PCR testing, as they vary in sensitivity (58-100%) and specificity (60-100%). The document advises on proper test selection, storage, training, and integration into national surveillance systems to enhance cholera response efforts.
more
The GTFCC Laboratory Support for Public Health Surveillance document provides guidelines on using DNA-based molecular techniques for identifying and monitoring Vibrio cholerae strains in cholera outbreaks. It highlights the importance of genetic sequencing for tracking transmission, detecting new va
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riants, and improving outbreak response. The report explains methods like PCR testing, whole genome sequencing (WGS), and multiple loci VNTR analysis (MLVA), detailing their advantages and applications. It also outlines best practices for sample collection, storage, and transportation, emphasizing collaboration between national and international laboratories to enhance cholera surveillance and control efforts.
more
The WHO Cholera Rapid Diagnostic Test (RDT) Target Product Profile outlines the key requirements for developing improved cholera RDTs. It highlights the need for fast, accurate, and easy-to-use tests for early outbreak detection in resource-limited settings. The document sets desired and acceptable
...
performance criteria, including high sensitivity and specificity, rapid results (under 15 minutes), and usability by non-laboratory personnel. The tests should be affordable, stable in extreme conditions, and require minimal training. The goal is to enhance cholera surveillance and outbreak response, ensuring quick containment and improved public health outcomes.
more
Drawing on lessons from recent events, WHO launched ‘PRET - Preparedness and Resilience for Emerging Threats’ to support countries in updating their pandemic plans. Building on the current global momentum, PRET applies a “mode of transmission lens.”
The first PRET module focuses on preparin
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g for respiratory pathogens. Future modules will focus on other pathogen groups such as arthropod-borne viruses.
more
The document outlines the 2017 cholera outbreak in Zambia, mainly in Lusaka, due to poor sanitation and unsafe water. By December, 493 cases were reported, with risks increasing due to the rainy season. The Zambia Red Cross Society (ZRCS), in collaboration with the Ministry of Health, WHO, and UNICE
...
F, responded by setting up treatment centers, supplying clean water and chlorine, and conducting hygiene education. 1,500 volunteers were mobilized to support 70,000 people directly. The IFRC allocated CHF 222,351 to control the outbreak, but challenges like limited funding and poor infrastructure remained.
more
WHO supports Zambia in vaccinating 1 million people in Lusaka against cholera to combat an outbreak that began in October 2017, causing 2,672 cases and 63 deaths. Two million vaccine doses were provided by Gavi. WHO and the Zambia National Public Health Institute are improving water access, sanitati
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on, and hygiene education while training medical staff. Another 1 million people in high-risk areas will be vaccinated later.
more
The study on single-dose cholera vaccine in Zambia evaluates the effectiveness of using a single dose of the oral cholera vaccine (OCV) during a 2016 outbreak in Lusaka. Due to limited vaccine supply, authorities opted for a one-dose emergency campaign instead of the usual two-dose regimen. A matche
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d case-control study was conducted to assess vaccine effectiveness, showing 88.9% short-term protection against cholera. The findings suggest that a single-dose approach can be an effective strategy in outbreak settings, especially when vaccine supplies are constrained. However, further research is needed to determine long-term immunity and effectiveness in young children.
more
Une liste de contrôle pour le nettoyage et la décontamination des terminaux destinés aux établissements de soins pour les patients atteints d'Ebola doit inclure le nettoyage et la désinfection minutieux de toutes les surfaces, l'élimination et le traitement approprié des articles contaminés,
...
ainsi que la désinfection de l'ensemble de la zone, y compris les endroits difficiles d'accès, à l'aide de méthodes et de produits appropriés.
more
The Zimbabwe Multi-Sectoral Cholera Elimination Plan (2018–2028) aims to eradicate cholera by improving water, sanitation, and healthcare infrastructure, strengthening disease surveillance, and expanding oral cholera vaccination (OCV). The strategy focuses on five pillars, including public health
...
response, WASH, infrastructure, community empowerment, and financing. A multi-sectoral approach involving government, international organizations, and local communities targets cholera hotspots to prevent outbreaks and ensure long-term disease control.
more
A cólera é uma infecção intestinal provocada por uma bactéria conhecida como Vibrio cholerae. Os principais sintomas desta doença são diarréia e vômitos. Transmissão de cólera ocorre principalmente pelo consumo de alimentos contaminados ou água potável. Neste vídeo descrevemos várias
...
técnicas que podem ser utilizadas para ajudar a prevenir a cólera.
more
The exercise was convened by the East Africa Community (EAC) and implemented by the World Health Organization (WHO) to test both countries’ preparedness and response to disease outbreaks. It covered various real-life simulations involving the health, livestock, agriculture, tourism and environment
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sectors. The simulation that was presented was not unusual in the region, and highlighted the daily challenge of managing the risk of disease outbreaks.
more
The WHO Framework for the clinical evaluation of devices for male circumcision
outlines a multi-phase process to ensure the safety, efficacy, and acceptability of new devices, especially for use in resource-limited settings
These guidelines are intended for use by health care workers responsible for performing MMC, as well as DoH officials, nongovernmental organizations
The List of WHO-prequalified Male Circumcision Devices contains male circumcision devices for adult male populations, appropriate for use in resource-limited settings
Report of the WHO Technical Advisory Group | 12 August 2016 | Geneva, Switzerland
COVID-19 Simulation Exercises Packages
recommended
To support countries’ preparedness effort on the COVID-19 outbreak, the Department of Health Security Preparedness at the WHO headquarters has developed various COVID-19 tabletop exercise (TTX) and Drills (DR) packages .
If you need technical support to implement any of the exercises listed on th
...
is page, please contact your WHO country office or regional office focal point.
more
What you should do as head of school or child centre to prevent cholera:
Educate all staff and pupils on the common cholera transmission routes and how to prevent it.
Educate all kitchen staff on how to handle food and cooking utensils. Emphasis the key points below:
o All kitchen staff MUST wa
...
sh their hands with soap and chlorine solution before cooking or handling food.
o All food should be properly stored to prevent contamination from insects etc.
o Wash all food in safe water.
o All food served should be properly cooked, and served hot.
o Only allow kitchen staff to enter the kitchen and to serve food.
o Wash dishes with soap or chlorine solution and rinse under safe water. Dry dishes on a rack well above the ground and in the direct sunlight (sunlight will help to disinfect).
All students should wash their hands with soap and safe water or chlorine solution before eating
Avoid washing your hands in a bowl of standing water, always use safe, running water!
more
