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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Integrated Disease Surveillance and Response - District Level Training Course - Facilitator Guide

World Health Organization; Regional Office for Africa (2011)

The Facilitator's Guide provides instruction and suggestions for teaching the training modules for the Technical Guidelines for Integrated Disease Surveillance and Response in the Africa Region, 2nd edition. This training is intended for district level health officers who conduct IDSR activities. Th... more

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A study on children with disabilities and their right to education: Republic of Rwanda

United Nations Children's Fund (UNICEF), Education Development Trust, Ministry of Education in Rwanda (MINEDUC) (2016) C2

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Challenging disadvantage in Zambia: People with psychosocial and intellectual disabilities in the criminal justice system

The PAN, the Mental Health Users Network Zambia (MHUNZA), the Prisons Care and Counselling Association (PRISCCA), et al. Open Society Initiative for Southern Africa (OSISA) (2015) C1

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Philippine Practice Guidelines on the Diagnosis and Management of Diabetes Mellitus

UNITE FOR DIABETES PHILIPPINES (2010) C1

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Severe Acute Malnutrition Update: Current WHO Guidelines and the WHO Essential Medicine List for Children

Williams, Phoebe CM.; Berkley, James A. (2016) C1

This document was prepared in response to a need to review and potentially update the current recommendations for the antibiotic treatment of both inpatient and outpatient management of severe acute malnutrition (SAM). The current recommendations (Table 1) are based on guidelines published in 2013 i... more

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Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infection and Interventions to Reduce Perinatal HIV Transmission in the United States

Development of Health and Human Services USA; AIDSinfo Development of Health and Human Services USA; AIDSinfo (2020) C2

Developed by the HHS Panel on Treatment of Pregnant Women with HIV Infection and Prevention of Perinatal Transmission— A Working Group of the Office of AIDS Research Advisory Council (OARAC) Accessed: 12.02.2020

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World Drug Report 2019 Booklet 5 Drugs and the environment

United Nations Office on Drug and Crime UNODC (2022) C2

The booklet starts with a general overview of how illicit drugs and the environment are linked within the bigger picture of the Sustainable Development Goals, climate change and environmental sustainability. It highlights direct and indirect linkages and gives examples of the significant local and i... more

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Caught in Crossfire - Children and education in regions affected by civil strife

Save the Children (2013) C2

This study primarily aims to understand how children living in areas of civil strife are denied their basic rights, especially the right to education and protection. For this study, eight districts affected by civil strife across the three states (Chhattisgarh: Dantewada, Bijapur, Bastar and Narayan... more

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Cambodia Health System Review: The current policies and strategies of the health system’s governance, financing, and service delivery

Steve Peat SFU MPH Capstone Project (2013) CC

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The increasing burden of diabetes and variations among the states of India: the Global Burden of Disease Study 1990–2016

India State-Level Disease Burden Initiative Diabetes Collaborators (2018) CC

Lancet Glob Health 2018, Published Online September 12, 2018 http://dx.doi.org/10.1016/S2214-109X(18)30387-5

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Bipolar in children and adolescents

R. S. Diler; B. Birmaher IACAPAP (2012) C2

Mood disorders Chapter E.2

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Principles to guide health system recovery and transformation in Ukraine

World Health Organization WHO (2022) C_WHO

Despite the continuing war in Ukraine, the Government is preparing for the country’s recovery and reconstruction. Given the magnitude of the attacks on the health infrastructure and consequent disruption to health system functioning, reconstruction of the health system is integral to the country�... more

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The OIE Strategy on Antimicrobial Resistance and the Prudent Use of Antimicrobials

World Organisation for Animal Health (2016) C2

The OIE has been working on the AMR issue for a long time. In undertaking its role as a standard- setting organisation* for animal health, including zoonoses, the OIE has developed a wide range of international standards on antimicrobial agents, in particular on responsible and prudent use. The... more

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Standard Treatment Guidelines and Essential Medicines List for South Africa : Primary Healthcare Level 2020 edition

the Essential Drugs Programme, the PHCAdult Hospital Level Expert review Committee, the National Essential Medicines List Committee National Department of Health South Africa (2020) CC

The PHC STGs and EML should be used by healthcare workers providing care at clinics, community health centres, and gateway clinics at hospitals. Pharmaceutical and Therapeutics Committees (PTCs) are responsible for ensuring the availability of medicines listed in the PHC EML at those facilities, as... more

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National Guidelines for Initiating and Managing Community -Based Family Planning Distribution (CBD) Services

Community Health Serivces Division and Family Health Division; Ministry of Health and Social Welfare Liberia USAID (2015)

Accessed February 2015

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COVID-19 Scientific and Public Health Policy Update – (6 July 2022)

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

This bi-weekly brief details the latest developments in scientific knowledge and public health policy from around the world as well as updates to the COVID-19-related guidance from Africa CDC, WHO and other public health agencies.

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To Stay and Deliver - Good practice for humanitarians in complex security environments

Jan Egeland, Norwegian Institute of International Affairs; Adele Harmer and Abby Stoddard, Humanitarian Outcomes Office for the Coordination of Humanitarian Affairs (OCHA) (2011) C2

The report offers an analysis of the broader challenges to securing humanitarian action and recommends areas for improvement. This study will contribute to improving the way humanitarians ‘do business’ in complex security environments. Document also available in French, Arabic and Spanish.

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European nurse: Information and communication guide on microbes

European specialist nurse organisation (ESN) (2020) C2

This manual addresses all the issues. It focus on the cycle of microbes, antibiotics, vaccination, AMR, infection prevention and control. It will support nurses on better action and also on communication towards their patients and families.

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WHO presence in countries, territories and areas: 2023 report

World Health Organisation (WHO) (2023) C_WHO

The 2023 Country Presence Report provides an overview of what WHO does in countries to advance towards the SDGs and implement GPW13, how we do it, with whom we work, and what is needed to overcome challenges for achieving results and impact in countries.