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Pediatric oncology nursing practice in Latin America and the Caribbean

Pan American Health Organisation PAHO (2024) C_WHO

One of the main aims of the WHO Global Initiative for Childhood Cancer and the CureAll Americas framework is to strengthen centers of excellence and promote the training of the health workforce, especially pediatric oncology nurses, specialized in nursing care for children and adolescents with cance ... more

Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for ... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

Health, rights and drugs - Harm reduction, decriminalization, and zero discrimination for people who use drugs

UNAIDS (Joint United Nations Programme on HIVAIDS) (2019) C2

Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy

World Health Organization WHO (2022) C_WHO

WHO’s sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy is intended for easy and frequent implementation. Results from sentinel surveys provide insight into the prevalence and year-over-year trends of dolutegravir resi ... more

Covid-19 in Brazil in 2020: impact on deaths from cancer and cardiovascular diseases

Cordeiro Jardim, B.; et al. (2022) CC

Rev Saude Publica. 2022; 56: 22. Published online 2022 Apr 11. doi: 10.11606/s1518-8787.2022056004040

Policy Paper The Inclusion of Persons with Disabilities in Financing for Development

International Disability Alliance (IDA) & International Disability Development Consortium (IDDC) (2014) C1

Key political commitment documents for tuberculosis prevention and care and their intended influence in the WHO European Region

World Health Organization WHO, Regional Office for Europe (2019) C_WHO

This analytical report reviews and discusses the potential role and influence of political commitment in implementing endorsements and conducting policy in the field of tuberculosis (TB) prevention and care. It promotes discussion by comparing and analysing the extent to which selected international ... more

The Sustainable Development Goals Report 2022

United Nations (2022) C2

According to the Report, cascading and interlinked crises are putting the 2030 Agenda for Sustainable Development in grave danger, along with humanity’s very own survival. The Report highlights the severity and magnitude of the challenges before us. The confluence of crises, dominated by COVID-19, ... more

WHO Guidance for Climate Resilient and Environmentally Sustainable Health Care Facilities
recommended

World Health Organization WHO (2020) C_WHO

The aim of this guidance is to enhance the capacity of health care facilities to protect and improve the health of their target communities in an unstable and changing climate; and to empower health care facilities to be environmentally sustainable, by optimizing the use of resources and minimizing ... more

Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV. Policy brief
recommended

World Health Organization WHO (2022) C_WHO

Cryptococcal disease, particularly cryptococcal meningitis is a significant cause of morbidity and mortality among people living with HIV with advanced HIV disease. It is estimated that it is responsible for nearly 19% of AIDS-related mortality, second only to tuberculosis. Rapid screening, diagnosi ... more

Integration of childhood TB into guidelines for the management of acute malnutrition in high burden countries

L. N. Patel,and A. K. Detjen The Union (2017) C2

Public Health Action PHA 2017; 7(2): 110–115

Behavioural considerations for acceptance and uptake of COVID-19 vaccines

World Health Organization WHO (2020) C_WHO

WHO technical advisory group on behavioural insights and sciences for health, meeting report, 15 October 2020

Responding to children and adolescents who have been sexually abused
recommended

World Health Organization WHO (2017) C_WHO

WHO clinical guidelines. For the first time, WHO has published guidelines to help (primarily) front-line healthcare providers give high-quality, compassionate, and respectful care to children and adolescents (up to age 18) who have or may have experienced sexual abuse, including sexual assault or r ... more

Tracking progress towards universal coverage for women’s, children’s and adolescents’ health

Ties Boerma, Jennifer Requejo, Cesar Victora et al. UNICEF; WHO, et al. (2018)

Addressing comorbidity between mental disorders and major noncommunicable diseases

World Health Organization WHO; Regional Office for Europe (2017) C_WHO

Reduced healthy life expectancy due to the high burden of both mental ill health and noncommunicable diseases (NCDs) is a major public health concern in the European Region. The links between mental disorders and major NCDs are well established. In clinical practice, however, mental disorders in pa ... more

Toolkit for research and development of paediatric antiretroviral drugs and formulations

World Health Organization (WHO); Unitaid; Unicef; et al. World Health Organization (WHO); Unitaid; Unicef; et al. (2018) C_WHO

WHO and UNITAID in collaboration with IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials) network, PENTA (Paediatric European Network for Treatment of AIDS) foundation and experts from the Paediatric Antiretroviral Working Group

What are relevant, feasible and effective approaches to promote acceptance, uptake and adherence to physical distancing measures for COVID-19 prevention and control?

Ryan, R.E.; et al. World Health Organization WHO, Regional Office of Europe (2021) C_WHO

Health Evidence Network synthesis report 72

Resource considerations for investing in hand hygiene improvement in health care facilities

World Health Organization WHO (2021) C_WHO

Investment in all the drivers and facilitators of hand hygiene action in health care to ensure that it occurs at the point of care and other critical moments requires a multidisciplinary, multifaceted approach. WHO describes such an approach as a “multimodal improvement strategy” (MMIS) which is ... more

Surgical care systems strengthening: developing national surgical, obstetric and anaesthesia plans

World Health Organization WHO (2017) C_WHO

Tuberculosis prevention and care among refugees and other populations in humanitarian settings: an interagency field guide
recommended

World Health Organization WHO, CDC, UNHCR (2022) C_WHO