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2025 is the first year of this century where child deaths will increase. But we can stop this reversal before it becomes a trend, even in a time of tight budgets. With proven solutions and next-generation innovations that do more with less, we can save millions of children's lives, protect the pro ... more
Addressing the threat of antimalarial drug resistance. This year’s report spotlights the growing threat of antimalarial drug resistance. Partial resistance to artemisinin derivatives – the backbone of malaria treatments after failures of chloroquine and sulfadoxine-pyrimethamine​ – has now b ... more
Malgré ces progrès, le paludisme reste toutefois un problème de santé mondial important, avec environ 282 millions de cas et 610 000 décès en 2024, soit environ 9 millions de cas de plus que l'année précédente. La région Afrique de l'OMS continue de supporter la plus grande partie du farde ... more
National Guidelines
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV document is published in an electronic format and updated as relevant changes in prevention and treatment recommendations occur.
Full Guidelines
Tuberculosis (TB) remains a serious public health threat in South Africa and is the leading cause of death in people living with HIV (PWH). Pre-hospital and early in- hospital mortality is of particular concern in PWH. Significant progress has been made to date, but a monumental effort is require ... more
This issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse ... more
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is highly dep ... more
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access ... more
A Training Curriculum
a comprehensive guide for the HCPs who work in counselling and psychological care of children and adoles- cents. The Handbook includes information on HIV clinical care; growth and development; mental health; child protection; counselling and communication; disclosure; loss, grief, and bereavemen ... more
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes organization of adolescent-friendly services to guide heath management teams and health care workers (HCWs) on their roles. It also outlines important aspects to consider when offering comprehensive care to adolescents an ... more
Journal of Adolescent Health 2022 1-16
A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context. The intention of this publication is to provide g ... more
Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un ... more