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Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and hea
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lthcare expenditure globally. Preventing the accumulation of cholesterol-containing atherogenic lipoproteins in the vessel wall is central to any healthcare strategy to prevent ASCVD. Advances in current concepts about reducing cumulative exposure to apolipoprotein B (apo B) cholesterol-containing lipoproteins and the emergence of novel therapies provide new opportunities to better prevent ASCVD. The present update of the World Heart Federation Cholesterol Roadmap provides a conceptual framework for the development of national policies and health systems approaches, so that potential roadblocks to cholesterol management and thus ASCVD prevention can be overcome.
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One of the first steps in developing a multisectoral action plan (MSAP) is to use a situation analysis to provide a comprehensive assessment of the health needs, prevailing risks and the context of the area to which the plan will apply. This will h
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elp countries, regions, provinces or cities intending to create a multisectoral action plan to align with the global commitments on targeting the four major NCDs: cardiovascular disease, diabetes, cancer and chronic respiratory diseases.
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This guidance synthesizes current evidence on dengue laboratory testing and diagnostics and provides practical recommendations for laboratories, clinicians, public health officials,
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and programme managers involved in dengue diagnosis, surveillance, and control, in the context of the global emergency. It includes a diagnostic algorithm for suspected cases, outlining appropriate testing methods based on days post symptom onset.
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The Gulf CDC Technical Guide for Rapid Risk Assessments of Acute Public Health Events provides a structured, multi-sectoral approach to evaluate and manage public health threats in Gulf Cooperation Council (GCC) countries. It focuses on rapid, evide
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nce-based assessments (within 2-5 days) to determine risk levels, propose control measures, and guide communications
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In one of his final essays, statesman and former United Nations secretary general Kofi Annan said, ‘Snakebite is the most important tropical disease you’ve never heard of’. Mr. Annan firmly believed that victims of snakebite envenoming should
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be recognised and afforded greater efforts at improved prevention, treatment, and rehabilitation. During the last years of his life, he advocated strongly for the World Health Organisation (WHO) and the global community to give greater priority to this disease of poverty and its victims.
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World malaria report 2025
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Addressing the threat of antimalarial drug resistance. This year’s report spotlights the growing threat of antimalarial drug resistance. Partial resistance to artemisinin derivatives – the backbone of malaria treatments after failures of chloroquine an
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d sulfadoxine-pyrimethamine – has now been confirmed or suspected in at least 8 countries in Africa, and there are potential signs of declining efficacy of some of the drugs that are combined with artemisinin.
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This summary brief highlights key messages from the updated World Health Organization’s recommendation on tranexamic acid (TXA) for the treatment of postpartum haemorrhage (PPH), including policy and program implications for translating the TXA re
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commendation into action at the country level. In 2012, WHO published recommendations for the prevention and treatment of postpartum haemorrhage, including a recommendation on the use of TXA for treatment of PPH. The 2017 updated WHO Recommendation on TXA is based on new evidence on use of TXA for treatment of PPH. This summary brief is intended for policy-makers, programme managers, educators and providers.
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Communities can play a critical role in suicide prevention. Facilitating community engagement in suicide prevention is an important task. The toolkit is a step-by-step guide for communities to engag
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e in suicide prevention activities and have ownership of the process and keep efforts sustained. It is hoped that the pilot version will be used, after necessary adaptation, in many countries and contexts, so that the final product can be strengthened and become more effective and user-friendly.
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The report provides an epidemiological update on cholera outbreaks in Haiti as of January 17, 2023. Since the first confirmed cases in October 2022, Haiti has reported 24,232 suspected cases, including 1,742 confirmed cases and 483 deaths. The most
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affected areas are in the Ouest Department, particularly Port-au-Prince. Children aged 1 to 4 years are the most affected group. The ongoing humanitarian crisis, security issues, and limited access to healthcare have worsened the outbreak, hindering epidemiological surveillance and case reporting. The PAHO/WHO is working with Haitian authorities to respond to the outbreak and mitigate its spread.
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This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
A new mobile learning courses developed by CapacityPlus lead partner IntraHealth International offer specialized guidance on care and prevention for health workers in Ebola-affected areas, delivered
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through SMS text messages or through interactive voice response on simple mobile phones. The reources will be available on the IntraHealth International website
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These guidelines focus on the provision of PrEP as part of comprehensive combination prevention,
drawing on implementation and research evidence and
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WHO recommendations.
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The brochure "How to Build Your Own Tippy Tap", published by SPRING in 2015, provides step-by-step instructions for creating a simple handwashing device called a tippy tap. It highlights the importance of hand hygiene and demonstrates how to constru
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ct the device using locally available, low-cost materials. The guide is designed to promote better hygiene practices in resource-limited settings, making handwashing with soap accessible and convenient.
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The document is a UNICEF cholera toolkit designed to support prevention, preparedness, and response to cholera outbreaks. It provides guidance on water sanitation, hygiene,
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and health education, along with practical tools and resources for managing outbreaks. It is intended for use by UNICEF teams, governments, and partners to integrate cholera prevention into development programs and emergency response strategies.
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Contact tracing is a key element of WHO’s recommended approach to control the spread of COVID-19 by breaking the chains of human-to-human transmission.
This document provides guidance to health authorities at all levels to improve the success rat
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e of contact tracing by informing efforts with RCCE principles, evidence and activities, and provides ready-to-use tools for professionals involved in contact-tracing efforts to inform their practices with RCCE principles and likewise improve their success rate.
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This document brings to attention key health and human rights considerations with regards to COVID-19 pandemic. It highlights the importance of integrating a human rights based approach in response to COVID-19. It provides key considerations in rela
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tion to addressing stigma and discrimination, prevention of violence against women, support for vulnerable populations; quarantine and restrictive measures and shortages of supplies and equipment. It also highlights human rights obligations with regards to global cooperation to address COVID-19.
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The pamphlet "What is Addiction" explains addiction as a chronic, relapsing brain disease characterized by compulsive drug seeking and use, despite harmful consequences. It highlights the dangers of different drug categories, including sedatives, st
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imulants, and hallucinogens, and their potential health and behavioral impacts. The document emphasizes the importance of combined medication and behavioral therapy in the treatment process, including detoxification, ongoing therapy, and relapse prevention. Additionally, it provides contact information for addiction treatment resources.
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Malaria in children presents significant clinical challenges, with variations in presentation based on the malaria parasite involved and the child's underlying health conditions. The World Health Organization reports high incidence rates, particular
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ly in sub-Saharan Africa, and emphasizes the importance of effective treatment strategies. First-line treatment often involves Artemether-Lumefantrine (ALu), while severe malaria requires careful management and the use of intravenous Quinine. Management protocols emphasize early diagnosis and the monitoring of severe complications to reduce mortality.
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In May 2015, the Sixty-eighth World Health Assembly recognized the importance of the public health problem posed by antimicrobial resistance by adopting the global action plan on antimicrobial resistance (“global action plan”). The global action plan proposes interve
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ntions to control antimicrobial resistance, including reducing the unnecessary use of antimicrobials in humans and in animals. The global action plan also emphasizes the need to take a cross-sectoral, “One Health” approach for controlling antimicrobial resistance, involving efforts by actors from many disciplines including human and veterinary medicine.
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The strategic plan reflects shared commitments to enhance collaboration between environmental, animal (wildlife and domestic) and human health, and
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building new One Health workforce capacity through higher institutions of learning. The strategy also outlines interventions to be undertaken by government institutions and other partners to enhance existing structures and pool together additional resources to prevent and control zoonotic diseases and other events of public health importance. Successful implementation of the strategy will contribute to the realization of vision 2020 by improving public health, food safety and security, and hence significantly improve the socioeconomic status of the people of Rwanda. It is in this regard that we call upon implementing institutions, bilateral and multilateral partners, civil society and the private sector to join us in implementing the One Health strategy in Rwanda.
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