WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches.
HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i...n randomized controlled trials or open-label studies. However, PrEP-selected HIV drug resistance could potentially negatively impact the effectiveness of treatment options among PrEP users who acquire HIV, since there is a potential for overlapping resistance profiles between antiretroviral drugs used for both PrEP and first-line antiretroviral therapy.
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Stop TB Communicable Diseases
Detailed adapted physical activities are provided with practical guides, group sport guides and assessment tools in order to promote a more inclusive society through sports
HIV drug resistance , Users Manual
December 2017
Unite for Children
First Edition
Ceci est la première version de la directive technique de l’INEE pour accompagner l’éducation pendant la pandémie de Covid-19. Ceci est un document évolutif qui sera régulièrement mis à jour pour répondre aux besoins d’apprentissage et de bien-être des enfants, des adolescents, des je...unes, des enseignants, des aidants et d’autres membres du personnel de l’éducation, affectés par le Covid-19.
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A Snapshot of European Collection Schemes
Ce modèle vise à aider les administrateurs des programmes nationaux de lutte contre le trachome à préparer
un dossier rassemblant les données factuelles à présenter à l’OMS pour solliciter la validation de l’élimination
de cette maladie en tant que problème de santé publique. Ces in...formations, qui recouvrent des données
épidémiologiques et des éléments sur le contexte général, aideront les responsables de l’examen à mieux
comprendre les résultats programmatiques.
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The Toolkit for Child Friendly Spaces in Humanitarian Settings was developed by
the International Federation of the Red Cross and Red Crescent Societies Reference
Centre for Psychosocial Support and World Vision International. The toolkit provides
a set of materials to assist managers and facilit...ators/animators in setting up and
implementing quality Child Friendly Spaces (CFS). These resources have at their core
the protection of children from harm; the promotion of psychosocial well-being; and
the engagement of community and caregiver capacities. The CFS Toolkit includes:
• Activity Catalogue for Child Friendly Spaces in Humanitarian Settings
• Operational Guidance for Child Friendly Spaces in Humanitarian Settings
• Training for Implementers of Child Friendly Spaces in Humanitarian Settings.
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The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
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