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1
2021 UNAIDS Global AIDS Update. UNAIDS report shows that people living with HIV face a double jeopardy, HIV and COVID-19, while key populations and children continue to be left behind in access to HIV services
Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are
...
limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
more
This report shows that increased domestic revenues can and will cover only part of the necessary SDG budget spending of the LIDCs. Achieving the SDGs in the LIDCs will also require increases of both Official Development Assistance (ODA) and Private Development Assistance (PDA) to reach aggregate lev
...
els of SDG-directed development aid on the order of US$300-400 billion USD per year
more
Background Note: Briefing to the Executive Board, First Regular Session 2025
The ECA, says over 300,000 Africans could lose their lives due to COVID-19. This, as the pandemic continues to impact on the Continent’s struggling economies whose growth is expected to slow down from 3.2 percent to 1.8 percent in a best-case scenario, pushing close to 27 million people into extr
...
eme poverty.
more
DR-TB drugs under the microscope: Sources and prices for drug-resistant tuberculosis medicines
recommended
Issue Brief 8th edition.
The present report is submitted pursuant to Security Council resolution 2164 (2014), by which the Council extended the mandate of the United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA) and requested me to report to it every three months on the implementation of the re
...
solution and the progress on the implementation of the Mission’s mandate. The present report covers the period from 17 December 2014 to 19 March 2015.
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Promoting the rights of children with disabilites in Malawi
Alister Munthali, Maxton Tsoka, James Milner, and Peter Mvula
UNICEF; Government of Malawi
(2012)
C1
From Exclusion to Inclusion
This report provides an update on the level of poverty based on 2013/14 Integrated Household Living Conditions Survey (EICV4) focusing on poverty as measured in consumption terms. The report also highlights other trend dimensions of living conditions captured in other surveys that complement and pro
...
vide a holistic understanding of poverty and living conditions.
Rwanda’s economy has been growing steadily at about 8% since 2001 with GDP per capita more than tripling from US$ 211 in 2001 to US$ 718 in 2014. Food crop production growth was more than twice that of population growth between 2007 and 2014.
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Руководство по лечению туберкулеза с множественной лекарственной устойчивостью
Kwonjune J. Seung, Michael L. Rich, Amy Elizabeth Barrera-Cancedda et al.
USAID, TBCARE I, TBCARE II
(2013)
C2
Это руководство предназначено для использования в качестве пособия дл яврачей и других медицинских работников, осуществляющих лечение и уход за больными лекарст
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енно-устойчивым туберкулезом.
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Original Article
SAGE Open Medicine Volume 5: 1–7 © The Author(s) 2017 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav httpDs:O//dIo: i1.o0r.g1/107.171/2770/52035013212171773311977 journals.sagepub.com/home/smo
Ending Aids - Progress towards the 90-90-90 targets
UNAIDS
(2017)
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Global AIDS Update 2017
A new publication - Waste Management during the COVID-19 Pandemic: from response to recovery - reviews current practices for managing waste from healthcare facilities, households and quarantine locations accommodating people with confirmed or suspected cases of COVID-19. Jointly produced by UNEP, th
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e Institute for Global Environmental Strategies and the International Environmental Technology Centre, the report considers various approaches, identifies best practices and technologies, and provides recommendations for policy-makers and practitioners to improve waste management, over the long term.
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Vaccines 2021, 9(2), 160; https://doi.org/10.3390/vaccines9020160