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Antimicrobials are medicines, including antibiotics, antivirals, antifungals, and antiparasitics, that are used to prevent and treat infections in humans, animals, and plants. Antimicrobial Resistance (AMR) arises when bacteria, viruses, fungi, and parasites no longer respond to these medicines, ren ... more
The present guidelines incorporate all these changes, leading to a substantial reconfiguration of therapeutic choices for both disease forms. HAT is a serious, life-threatening disease and the efficacy of fexinidazole depends on swallowing the medicine after an appropriate intake of food as well as ... more
This practical guideline establishes definitions for “contact”, “contact person”, “contact tracing” and other associated concepts. It allows for improvement of contact tracing strategies and provides recommendations attempting to answer some, though not all, questions that arose during t ... more
In this subsequent part of the issue brief on the NTD Toolbox you will learn about general strategies, roadmaps, key treatment guidelines, reports, and training material on Dengue & Chikungunya, Human African Trypanosomiasis and Leprosy.
UN GUIDE POUR L’APPROVISIONNEMENTEN MÉDICAMENTS/ A guide for drug supply Bochure in English and French
Overall, harmonisation and innovation should be the focus of the future direction of DAH and the creation of a healthy global community. The world needs all hands on deck if it were to move towards achieving the SDGs, addressing global health inequalities and improving the welfare of the global ... more
A historic funding crisis is threatening to unravel decades of progress unless countries can make radical shifts to HIV programming and funding. The report highlights the impact that the sudden, large-scale funding cuts from international donors are having on countries most affected by HIV. Yet it a ... more
This document highlights the latest WHO recommendations designed to optimize health outcomes, streamline delivery and address persistent barriers to prevention and care. It especially focuses on people often left behind in service delivery, including adolescents and young people, key populations and ... more
In the absence of a such a measure, and building on the success of developing the APCA African Palliative Outcome Scale (POS) for adults, the African Palliative Care Association has developed the APCA African Children’s POS. The tool has been validated across diseases, countries, settings and ... more
Updated guidance on the integration of diabetes, hypertension and mental health services, and interventions to support adherence to antiretroviral therapy. The guideline offers practical implementation guidance for countries and key stakeholders as well as outlining key research gaps. As life expec ... more
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to ... more
Technical Brief
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is highly dep ... more
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access ... more
a comprehensive guide for the HCPs who work in counselling and psychological care of children and adoles- cents. The Handbook includes information on HIV clinical care; growth and development; mental health; child protection; counselling and communication; disclosure; loss, grief, and bereavemen ... more
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact ... more
The guide presents a structured framework covering assessment and planning, service delivery models, integration with broader health and social services, monitoring, and sustainability. It emphasizes community leadership, human rights, equitable access and adaptation to local contexts, including clo ... more

Guideline: Adherence to antiretroviral therapy in adolescents and young adults (expanded version)

L. Fairlie; L. Jankelowitz; H. Ronald; et al. Southern African HIV Clinicians Society; Right to Care (Training Health Seriously) (2017) C2
Recommendations, resources and references A publication of the Southern African HIV Clinicians Society
Abrupt reductions in international HIV assistance in 2025 have deepened existing funding shortfalls. The OECD estimates that external health assistance is projected to drop by 30–40% in 2025 compared with 2023, causing immediate and even more severe disruption to health services in low- and middle ... more