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Toolboxes
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1
2023 was another year of significant progress in the fight against HIV, tuberculosis (TB) and malaria. In countries where the Global
Fund invests, there has been a full recovery from the disruptive impact of the COVID-19 pandemic. The results we have achieved in the last year build on our extraord
...
inary track record of progress. Over the last two decades, our partnership has cut the combined death rate from AIDS, TB and malaria by 61%. As of the end of 2023, the Global Fund partnership has saved 65 million lives.
more
The 2022 report reviews the global malaria diagnostics market and technological landscape to support Unitaid’s 2023–2027 strategy for quality malaria case management. The report highlights the stalled progress of malaria control efforts, the gaps in access to diagnostics and the public health im
...
plications of P. falciparum HRP2/3 gene deletions, which compromise the accuracy of the widely used HRP2-detecting rapid diagnostic tests (RDTs). The report analyses the malaria RDT market, noting supplier diversification, price trends and production shifts resulting from the pandemic. It also addresses the emerging point-of-care G6PD testing market, which is required to ensure the safe radical cure of P. vivax infections. It surveys technological innovation, including digital microscopy, hemozoin tests, nucleic acid detection and biosensors, while emphasising that RDTs and microscopy will remain the mainstay of case management in the near term. The report identifies market shortcomings, access barriers and opportunities to improve malaria case management and diagnostic coverage.
more
In conclusion, the current evidence does not support the use of mpox antigen RDTs in the field. More data are expected from independent evaluations conducted by Africa CDC, FIND or other organizations
On 4 September 2025, the Ministry of Health of the Democratic Republic of the Congo (DRC) declared an outbreak of Ebola Virus Disease (EVD) in Kasai Province, following confirmation of Zaire ebolavirus by the National Institute of Biomedical Research (INRB) in Bulape and Mweka Health Zones. As of 19
...
September, there have been 48 total cases (38 confirmed, 10 probable) with 31 deaths (21 confirmed, 10 probable) and a CFR of 64.5%. Among laboratory confirmed cases, 16 deaths were recorded (CFR: 45.7%). Four deaths occurred among health workers, underscoring the risk of nosocomial transmission. Most cases (39.7%) are among adults aged 20 years and above, in a densely populated, remote, and under-resourced area.
The outbreak is driven by multiple risk factors, including transmission in health facilities with limited infection prevention and control (IPC) measures and personal protective equipment (PPE), incomplete contact tracing, delayed detection, and unsafe burial practices. High population mobility between Bulape and Tshikapa, reliance on traditional healers, and the concurrent mpox outbreak are further straining the fragile health system and increasing the risk of geographic spread.
more
HIV testing is an essential health service and a gateway to lifesaving treatment and high-impact strategies that
stop new HIV infections. However, reductions in international funding for global health—including national HIV programs—are causing disruptions in service delivery. This FAQ, develop
...
ed alongside the 12 May WHO-PSI webinar, offers practical guidance for countries aiming to sustain HIV testing services by implementing cost-effective and differentiated strategies.
more
Measles is one of the most contagious diseases for humans. It is caused by a paramyxovirus virus, manifesting as a febrile rash illness. The incubation period for measles usually is 10–14 days (range 7–23 days) from exposure to symptom onset. Initial symptoms (prodrome) generally consist of feve
...
r, malaise, cough, conjunctivitis, and coryza. The characteristic maculopapular rash appears two to four days after onset of the prodrome. Patients are usually contagious from about four days before rash onset until four days after its appearance.
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The guidelines present and discuss new recommendations and consolidate a range of recommendations and guidance from current WHO guidelines which are summarised here in this policy brief.
Policy brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for trans and gender diverse people.
Polic brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for men who have sex with men.
Policy brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for sex workers
The UNICEF Gender Equality Action Plan, 2026–2029 provides the road map
for the organization’s key commitments to advancing gender equality and the
empowerment of all girls and women, anchored in the UNICEF Strategic Plan,
2026–2029.
The standards of care for HIV define the expected or desired quality of prevention, treatment, and care for people at risk of HIV acquisition or living with HIV.
The standards are based on a scientific rationale, as well as the responsibilities of each stakeholder, to ensure that people receive app
...
ropriate, high-quality prevention and care that aligns with the most up-to-date medical knowledge and ethical standards
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Internal Document
What works?
Bhana A et al. Journal of the International AIDS Society 2021, 24(S2):e25713
Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un
...
ited Arab Emirates, Yemen.
To support countries in the region to achieve triple elimination goals, this report collects and assesses national policies and key indicators on EMTCT efforts against WHO criteria for validation of the EMTCT of HIV, syphilis and HBV. Based on analysis and consultations with national policymakers, the report provides a Road Map for countries at different stages of readiness to follow towards triple elimination goals.
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A service guide for site operations
The document “Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa” outlines a coordinated strategy developed by Africa CDC to improve public health surveillance and collaboration across national borders in Africa. It addresses the challenge that infe
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ctious diseases often spread across borders due to population movement, trade, and migration, while surveillance systems and data-sharing mechanisms frequently remain nationally focused and fragmented.
The framework proposes strengthening regional coordination, harmonizing surveillance systems, enhancing information sharing between countries, and building laboratory and workforce capacity. It also emphasizes timely detection of cross-border health threats, joint outbreak investigations, and improved communication among Member States. Overall, the document aims to enhance preparedness, early warning systems, and collective response to public health threats across the African continent.
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Paving the Way for One Health: Highlights of the Global Programme Pandemic Prevention and Response, One Health
Haensel L., Argote K., Stübel E.
Deutsche Gesellschaft für Internationale Zusammenarbeit GIZ
(2024)
CC
The document “Paving the Way for One Health: Highlights of the Global Programme Pandemic Prevention and Response, One Health” presents the work and achievements of the global programme implemented by the German development agency GIZ to strengthen pandemic prevention using the One Health approac
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h. The report highlights how collaboration between the human health, animal health, and environmental sectors can help detect and prevent zoonotic diseases before they spread. It describes activities carried out in partner countries, such as improving surveillance systems, strengthening laboratory capacities, supporting cross-sector cooperation, and building the skills of health professionals. The document also showcases practical examples and project results that demonstrate how integrated One Health strategies contribute to better preparedness and more effective responses to future health threats. Overall, the report illustrates how international cooperation and interdisciplinary approaches can reduce the risk of pandemics and improve global health security.
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PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920. PLHIV were largely unaware and sceptical of U = U as the message appeared to contradict
the mainstream HIV prevention clinical guidance.
