La publicación es el resultado de la participación de diversos actores sociales involucrados activamente en la lucha contra la tuberculosis, en el marco de la VIII Ronda del Fondo Mundial de lucha contra el SIDA, la tuberculosis y la malaria, que busca a través de una metodología participativa c...apacitar, e integrar los nuevos conocimientos y destrezas al uso cotidiano del personal de salud a fin de sumar acciones de lucha en favor de la adherencia.
more
National Operational Guidelines
Decree of the Minister of Health of the Republic of Indonesia Number 122 / MENKES / SK / IX / 2002 on the establishment of coordination committee of AIDS, tuberculosis and malaria in Indonesia
Ministrial Meeting Towards Ending TB in the South-East Asia, 15-16 March 2017, New Dehli India
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
more