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South African cardiovascular risk stratification guideline for non-cardiac surgery

Alphonsus, C.; Naidoo, N.; Motshabi, P. et al. South African Medical Journal (2021) CC

The South African (SA) guidelines for cardiac patients for non-cardiac surgery were developed to address the need for cardiac risk assessment and risk stratification for elective non-cardiac surgical patients in SA, and more broadly in Africa. The guidelines were developed by updating the Canadian ...Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Non-cardiac Surgery, with a search of literature from African countries and recent publications. The updated proposed guidelines were then evaluated in a Delphi consensus process by SA anaesthesia and vascular surgical experts. The recommendations in these guidelines are: 1. We suggest that elective non-cardiac surgical patients who are 45 years and older with either a history of coronary artery disease, congestive cardiac failure, stroke or transient ischaemic attack, or vascular surgical patients 18 years or older with peripheral vascular disease require further preoperative risk stratification as their predicted 30-day major adverse cardiac event (MACE) risk exceeds 5% (conditional recommendation: moderate-quality evidence). 2. We do not recommend routine non-invasive testing for cardiovascular risk stratification prior to elective non-cardiac surgery in adults (strong recommendation: low-to-moderate-quality evidence). 3. We recommend that elective non-cardiac surgical patients who are 45 years and older with a history of coronary artery disease, or stroke or transient ischaemic attack, or congestive cardiac failure or vascular surgical patients 18 years or older with peripheral vascular disease should have preoperative natriuretic peptide (NP) screening (strong recommendation: high-quality evidence). 4. We recommend daily postoperative troponin measurements for 48 - 72 hours for non-cardiac surgical patients who are 45 years and older with a history of coronary artery disease, or stroke or transient ischaemic attack, or congestive cardiac failure or vascular surgical patients 18 years or older with peripheral vascular disease, i.e. (i) a baseline risk >5% for MACE 30 days after elective surgery (if no preoperative NP screening), or (ii) an elevated B-type natriuretic peptide (BNP)/N-terminal-prohormone B-type natriuretic peptide (NT-proBNP) measurement before elective surgery (defined as BNP >99 pg/mL or a NT-proBNP >300 pg/mL) (conditional recommendation: moderate-quality evidence). Additional recommendations are given for the management of myocardial injury after non-cardiac surgery (MINS) and medications for comorbidities. more

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Effectiveness of community health worker training programmes for cardiovascular disease management in low-income and middle-income countries: a systematic review

Abdel-All, M; Putica, B.; Praveen, D. et al. BMJ Open (2017) CC

Introduction Community health workers (CHWs) are increasingly being tasked to prevent and manage cardiovascular disease (CVD) and its risk factors in underserved populations in low-income and middle-income countries (LMICs); however, little is known about the required training necessary for them to ... more

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Projecting the risk of mosquito-borne diseases in a warmer and more populated world: a multi-model, multi-scenario intercomparison modelling study

Colón-González, F.J.; M. Odhiambo Sewe, A.M Tompkins et al. The Lancet (2021) CC

Mosquito-borne diseases are expanding their range, and re-emerging in areas where they had subsided for decades. The extent to which climate change influences the transmission suitability and population at risk of mosquito-borne diseases across different altitudes and population densities has not be... more

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Zambia: Drought (Food Insecurity) Emergency Appeal n° MDRZM012

International Federation of Red Cross And Red Crescent Societies IFRC (2019) C1

A “catastrophic” combination of drought and communities’ declining resilience has left an estimated 2.3 million people facing severe acute food insecurity – up from an estimate of 1.7 million people a month ago. Communities across southern Africa have been affected by drought since late 2... more

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Donor Funding for Newborn Survival: An Analysis of Donor-Reported Data, 2002–2010

Pitt1, C.; J. E. Lawn; M. Ranganathan et al. PLoS Med (2012) CC

Background:Neonatal mortality accounts for 43% of global under-five deaths and is decreasing more slowly than maternal or child mortality. Donor funding has increased for maternal, newborn, and child health (MNCH), but no analysis to date has disaggregated aid for newborns. We evaluated if and how a... more

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European inventory of national policies for the prevention of violence and injuries

World Health Organization WHO (2014) C_WHO

This inventory has been compiled by WHO/Europe to help facilitate monitoring and reporting of national policies for the prevention of violence and injuries, in close collaboration with national focal persons officially nominated by ministries of health and with support from the European Commission (... more

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Malaria chemoprevention efficacy study protocol

World Health Organization WHO (2022) C_WHO

Chemoprevention is the use of medicines, either alone or in combination, to prevent malaria infection and its consequences. This publication provides standardized approaches for monitoring and evaluating the efficacy of medicines used for intermittent preventive treatment of malaria in pregnancy, pe... more

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2018-2019 Mozambique Humanitarian Response Plan (November 2018 - June 2019) - Revised following Cyclone Idai, March 2019
recommended

UN Office for the Coordination of Humanitarian Affairs, UN Resident Coordinator for Mozambique, UN Country Team in Mozambique (2019) C1

While the full extent of Cyclone Ida’s impact is still being assessed, early reports indicate significant damage to infrastructure and livelihoods, with an estimated 3,000km2 of land submerged. Preliminary government reports as of 24 March indicate that more than 58,600 houses have been damaged, i... more

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Considerações sobre o impacto da covid-19 na relação indivíduo-sociedade: da hesitação vacinal ao clamor por uma vacina

Couto,M.T.; Carolina L.A. Barbieri, C. Carvalho de Souza Amorim Matos (2021) CC

Saúde Soc. São Paulo, v.30, n.1, e200450, 2021 Desde março de 2020, quando a Organização Mundial de Saúde declarou que o mundo vivia uma pandemia de covid-19, acompanhamos um quadro sanitário sem precedentes nos últimos 100 anos. As medidas atuais contra a ... more

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Burden of Severe Fungal Infections in Burkina Faso

Bamba S. , Zida A., Sangaré I. et al. Journal of Fungi (2018) CC

Because of the limited access to more powerful diagnostic tools, there is a paucity of data regarding the burden of fungal infections in Burkina Faso. The aim of this study was to estimate the incidence and prevalence of serious fungal infections in this sub-Saharan country. We primarily used the na... more

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Southeast Asia One Health University Network

Southeast Asia One Health University Network (2022) CC

The spillover of infectious agents from animals to humans in recent decades has had a significant impact on the health of humans, animals, and our environment. To minimize the impact of future pandemic threats, the Southeast Asia One Health University Network (SEAOHUN) was established in 2011 to dev... more

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App: Open Guidelines

Loetz, S. Department of pediatrics; Queen Elizabeth Central Hospital in Blantyre, Malawi. (2017) CC

Open Guidelines is brought to you on behalf of the paediatrics department of Queen Elizabeth Central Hospital in Blantyre, Malawi. Our aim is to improve access to clinical guidelines for our health care professionals. Open guidelines has all the latest QECH clinical protocols and essential drug i... more

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Ukraine: Escalation of attacks across the country, Situation Report 26 October 2022
recommended

United Nations Office for the Coordination of Humanitarian Affairs OCHA (2022) C2

Highlights (1 week ago) - Civilians have been killed and injured in ongoing fighting while attacks on infrastructure have left people without heat or water. - Declaration of “Martial law” in Donetska, Khersonska, Luhanska and Zaporizka oblasts creates concern over access and movements for ci... more

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Global patient safety action plan 2021–2030: towards eliminating avoidable harm in health care

World Health Organisation (WHO) (2022) C_WHO

Today, patient harm due to unsafe care is a large and growing global public health challenge and is one of the leading causes of death and disability worldwide. Most of this patient harm is avoidable. As countries strive to achieve universal health coverage and the Sustainable Development Goals, t... more

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COVID-19 Open Research Dataset (CORD-19)

Allen Institute for AI ; Semantic Scholar (2020) CC

A Free, Open Resource for the Global Research Community In response to the COVID-19 pandemic, the Allen Institute for AI has partnered with leading research groups to prepare and distribute the COVID-19 Open Research Dataset (CORD-19), a free resource of over 51,000 scholarly articles, including ov... more

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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PAHO Zika database

Pan American Health OrganizationWorld Health Organization (2016) C_WHO

PAHO has systematically identified and collected basic information on all investigations related to Zika, both those already published and those on track to be published. Each study has been categorized in the areas of virus, vectors and reservoirs; epidemiology; disease pathogenesis and consequen... more

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Multiple-hazards and systemic risk: Addressing climate-related disasters in times of COVID-19

UN office for Disaster Risk Reduction (2020) CC

The current effort on fighting COVID-19 cannot conceal the fact that climatic and geological hazards affect Latin-America and the Caribbean every year. At a time when countries of the region are actively responding to the pandemic, they also need to prepare for and implement actions to mitigate the ... more

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Using social media to disseminate COVID-19 Information

USAID (2020) CC

A Technical Brief for Breakthrough ACTION Field Teams Social media can be used to collect and address rumors or popular beliefs among target audiences, share evidence-based and timely health information, receive instant feedback on materials, conduct remote trainings, promote awareness of a project... more

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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies

Alipanah N, Jarlsberg L et al. (2018) CC

We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro... more

2018-2019 Mozambique Humanitarian Response Plan (November 2018 - June 2019) - Revised following Cyclone Idai, March 2019 recommended

Ukraine: Escalation of attacks across the country, Situation Report 26 October 2022 recommended

2018-2019 Mozambique Humanitarian Response Plan (November 2018 - June 2019) - Revised following Cyclone Idai, March 2019
recommended

Ukraine: Escalation of attacks across the country, Situation Report 26 October 2022
recommended