This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita...ls in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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Prepared as an outcome of ICMR Subcommittee on Multiple Myeloma | This consensus document on management of multiple myeloma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also i...nterweaves clinical, biochemical and epidemiological studies.
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(version 1.0): procedure: methods manual
Alto a la Tuberculosis.
Enfermedades Transmisibles.
Esta publicación integra la experiencia acumulada de la OPS y las buenas prácticas desarrolladas por sus Estados Miembros en los últimos años, incluidas las discusiones y experiencias compartidas en las reuniones regionales celebradas sobre el tema, y pone el acento en la innovación y la inclus...ión social. Esto requiere cambiar con urgencia los paradigmas tradicionales, partiendo de las acciones específicas que reducen gradualmente la incidencia de la TB para dirigirnos hacia acciones multisectoriales de eficacia demostrada en la contención rápida de la epidemia.
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Embracing Diversity: Toolkit for Creating Inclusive, Learning-Friendly Environments Specialized Booklet 3
Prepared as an outcome of ICMR Subcommittee on Colorectal Cancer | Coordinated by Division of Non Communicable Diseases | This Consensus Document on Management of Colorectal Cancer summarizes the modalities of treatment including the site-specific anti-cancer therapies,
supportive and palliative ca...re and molecular markers and research questions. It also interweaves clinical, biochemical and epidemiological studies.
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The objectives of this guidance document are to:
1. Strengthen the capacity of country teams to effectively scale up and manage programmes to address severe acute malnutrition
2. Extend the geographic reach of quality treatment for SAM to all vulnerable communities in need
3. Maximize... access to appropriate and quality treatment for SAM among all eligible children in the community at all times
4. Aid the formulation and implementation of national policies and strategies that support objectives 1 to 3
5. Aid the creation of an enabling environment that supports objectives 1 to 3 through advocacy, documentation of successful practices, support for operational research, mobilization of resources and collaboration with partners
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La estrategia está basada en los pilares del desarrollo comunitario centrado en la niñez, y su éxito se medirá por la forma en que los países contribuyen con sus sistemas de protección de la niñez y se asocian a varios niveles para combatir la violencia contra la niñez. Esta estrategia es e...l resultado de un proceso altamente consultivo que abarcó a los niños, niñas y jóvenes, personal de Plan International, especialistas externos a nivel global, y el documento ha sido elaborado con los esfuerzos conjuntos del grupo de referencia de programas de protección de la niñez.
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Background paper prepared for theEducation for All Global Monitoring Report 2012 Youth and skills: Putting education to work
2012/ED/EFA/MRT/PI/15
Religion and Development 01/2019. Discussion Paper Series of the Research Programme on Religious Communities and Sustainable Development
Meeting of the Neglected Tropical Diseases Strategic and Technical Advisory
Group’s Monitoring and Evaluation Subgroup on Disease-specific Indicators
Crecer bien en un mundo en transformación
Singing to the Lions es un paquete de capacitación gratuito (guía del facilitador, suplemento y video) de CRS, que está diseñado para ayudar a los niños y jóvenes a disminuir el impacto de la violencia y el abuso en sus vidas. El componente principal es un taller de tres días en el que los pa...rticipantes aprenden habilidades que pueden ayudarlos a transformar sus vidas y ya no sentirse dominados por el miedo. Aunque el taller está dirigido a jóvenes e incluye juegos, arte y canciones, también se puede utilizar para ayudar a los adultos a tomar medidas en aspectos de sus vidas que causan miedo y, al hacerlo, convertirse en mejores padres y cuidadores.
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Sepsis remains a leading cause of mortality and morbidity, especially during the first five days of life and in low and middle-income countries (LMIC) [1]. Hospital infection also remains a major cause of mortality in children despite progress encountered in the last decades.
Global UNIDO Project: Strengthening the local production of essential generic drugs in the least developed and developing countries
based on the WHO Bench Aids for the diagnosis of intestinal parasites;
Tutor’s Guide: perform specific laboratory techniques; identify intestinal parasites by genus and species; quantify helminth eggs in faeces by Kato-Katz procedure.