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Pregnancy often results in exclusion from clinical trials of antiretroviral (ARV) drugs, resulting in limited data on pharmacokinetics (PK), drug safety, and the efficacy of new ARV drugs in pregnan
...
cy and lactation. However, pregnancy, lactation, or the potential for pregnancy should not preclude the use of drug regimens that would be chosen for people who are not pregnant, unless adequate drug levels are not likely to be attained in pregnancy or known adverse effects outweigh potential benefits
more
Detailed clinical guidelines focusing on dolutegravir-based regimens.
Stats SA has released an in-depth report on persons with disabilities. The report, written using Census 2011 data, is the first in a series of in-depth analyses of various Census 2011 variables, suc
...
h as ageing and education.
The report provides statistical evidence relating to the prevalence of disability and characteristics of persons with disabilities at both individual and household levels. Two methods were used to profile disability prevalence and patterns based on the six functional domains, namely seeing, hearing, communication, remembering/concentrating, walking and self-care. These two methods were:
- the level/degree of difficulty in a specific functional domain and;
- the disability index.
more
HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexualit
...
y; stigma and discrimination; gender discrimination; violence; lack of community empowerment and other violations of human rights. These sociostructural factors limit access to health services, constrain how these services are
delivered and diminish their effectiveness.
more
Primary Care: The Community Health System
8–18 December 2015
This study of Adolescent Boys and Young Men highlights the importance of engaging adolescent boys and young men in sexual and reproductive health and rights (srhr) and gender equality. This paper e
...
stablishes a conceptual framework for engaging adolescent boys and young men. It reviews current research on boys’ and young men’s specific risks and realities in relation to their general health status, violence, sexuality and sexual and reproductive health, media violence, sexual exploitation, and other vulnerabilities.
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