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The Story of Cholera was produced in collaboration with award-winning animator Yoni Goodman.
This animation covers cholera transmission, prevention, signs,
...
and care in a simple and accessible way. The film follows evidence-based guidelines, has been field-tested, and reviewed for accuracy and content. Download flashcards and mobil phone versions from the website.
more
The Story of Cholera was produced in collaboration with award-winning animator Yoni Goodman.
This animation covers cholera transmission, prevention, signs,
...
and care in a simple and accessible way. The film follows evidence-based guidelines, has been field-tested, and reviewed for accuracy and content. Download flashcards and mobil phone versions from the website.
more
WHO updated recommendations on HIV clinical management: recommendations for a public health approach
recommended
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission,
...
and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to support global initiatives aimed at ending AIDS as a public health threat by 2030. Key changes include the introduction of new antiretroviral drugs and regimens, revised postnatal prophylaxis and breastfeeding guidelines for managing infants at risk of vertical transmission, and the endorsement of shorter tuberculosis preventive treatments to improve efficacy and adherence.
more
1.HIV infections – drug therapy. 2.Anti-HIV agents – adverse effects. 3.Anti-retroviral agents. 4.Benzoxazines – adverse effects. 5.Pregnancy. 6.Disease transmission, Vertical - prevention
...
and control. 7.Treatment outcome. I.World Health Organization
more
Microbes are living organisms that can be beneficial, neutral or harmful to humans. A basic understanding of microbiology will allow you to recognize how your role as an Infection Prevention and Con
...
trol (IPC) person can help break the cycle of transmission, prevent health care-associated infections (HAI) and reduce antimicrobial resistance (AMR).
more
Dengue is the fastest spreading, mosquito-borne viral infectious disease worldwide, with remarkable morbidity and mortality. In the past decades, profound contributions have been made towards understanding its epidemiology, including disease burden
...
and distributions, risk factors, and control and prevention practices. Dengue continues to disseminate to new areas, including high latitude regions, and a new serotype (dengue virus serotype 5) has been identified. Vaccine research has made new progress, in which the licensed yellow fever and dengue virus quadrivalent chimeric vaccine is now under further safety assessment. In disease surveillance, because of its operational simplicity, rapidity, capability, and utility as an indicator of disease severity, dengue virus NS1 antigen detection has great promotion and application value among primary health care institutions. Vector control progress has driven new breakthroughs in biotechnology, including Wolbachia-infected Aedes and genetically modified Aedes. Both Aedes variants have been used to block transmission of the dengue virus through population replacement and suppression. In the future, vector control should still be pursued as a key measure to prevent transmission, along with anti-viral drug and vaccine research.
more
This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help in tailoring optimal regimens for prevention of mother to child transmission of HI
...
V (pMTCT) and antenatal care.
more
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America. Chagas disease, as determined by the factors and determinants, shows
...
that different contexts require different actions, preventing new cases or reducing the burden of disease. Control strategies must combine two general courses of action including prevention of transmission to prevent the occurrence of new cases (these measures are cost effective), as well as opportune diagnosis and treatment of infected individuals in order to prevent the clinical evolution of the disease and to allow them to recuperate their health. All actions should be implemented as fully as possible and with an integrated way, to maximise the impact. Chagas disease cannot be eradicated due because of the demonstrated existence of infected wild triatomines
in permanent contact with domestic cycles and it contributes to the occurrence of at least few new cases. However, it is possible to interrupt the transmission of Trypanosoma cruzi in a large territory and to eliminate Chagas disease
as a public health problem with a dramatic reduction of burden of the disease.
more
The Global Leprosy Strategy 2021–2030 “Towards zero leprosy” was developed through a broad consultative process with all major stakeholders during 2019 and 2020. Valuable inputs were provided by national leprosy programme managers, technical a
...
gencies, public health and leprosy experts, funding agencies and persons or members of communities directly affected by leprosy.
The Strategy aims to contribute to achieving the Sustainable Development Goals. It is structured along four pillars:
(i) implement integrated, country-owned zero leprosy road maps in all endemic countries;
(ii) scale up leprosy prevention alongside integrated active case detection;
(iii) manage leprosy and its complications and prevent new disability; and
(iv) combat stigma and ensure human rights are respected. Interruption of transmission and elimination of disease are at the core of the Strategy.
more
Hygiene Awareness Manual (Arabic) - GIZ
recommended
The "Hygiene Awareness Manual" focuses on promoting improved hygiene practices within communities, emphasizing personal and household hygiene, water safety, and environmental health. It highlights t
...
he importance of handwashing, oral hygiene, and maintaining cleanliness of the skin and clothing as key aspects of personal and family hygiene. Specific practices such as regular bathing and wearing clean clothes are also emphasized.
For household hygiene, the manual provides guidance on safe food preparation and storage, as well as keeping living spaces, kitchens, and latrines clean to prevent contamination. It also addresses water safety, emphasizing the need to store water in clean containers, treat it for safe consumption, and dispose of wastewater properly to avoid environmental contamination.
The manual underscores the significance of balanced nutrition and food safety, offering guidelines for cooking and preserving food to reduce health risks. It also delves into disease prevention, explaining the causes and transmission of waterborne and hygiene-related diseases, such as cholera and dysentery, and outlining effective methods to prevent them through proper sanitation and hygiene.
This comprehensive guide serves as a practical resource for community health workers and households, aiming to foster better hygiene practices, prevent diseases, and enhance overall health and well-being.
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The webpage “Decontamination of Ambulances for Ebola Virus Disease (EVD)” provides guidance on how to safely clean and disinfect ambulances that have been used to transport suspected or confirmed Ebola patients. It outlines the procedures for de
...
contaminating vehicle surfaces, medical equipment, and potentially contaminated materials, while emphasizing the correct use of personal protective equipment (PPE) and infection prevention and control measures. The document aims to reduce the risk of Ebola transmission and ensure the safety of healthcare workers, ambulance personnel, and the public during outbreak response operations.
more
Cotonou declaration on buruli ulcer
recommended
Cotonou Declaration oBuruli Ulcer
Cotonou, Benin, 30 March 2009
Neglected tropical diseases kill, weaken or incapacitate millions of people every year, causing permanent physical suffering, social stigmatization and reduced productive capacity. Bu
...
ruli ulcer, one such disease, causes immense suffering and disabilities, especially among children. Delayed schooling and loss of productivity are considerable among the affected populations. These adverse consequences tend to aggravate poverty in affected communities. Globally, the disease has been reported in 30 countries. In WHO’s African Region, Buruli ulcer has been confirmed in 12 countries and is suspected in 10 others.
Significant progress has been made in the past 10 years in knowledge of Buruli
ulcer, investments in related research, control of the disease, and improvement
of tools for case diagnosis and development of treatment protocols. Substantial achievements have been made in diagnosis, treatment, immunology and epidemiology. Despite these achievements, little is known about the exact mode of transmission of the disease, and there is no simple diagnostic test usable in the field.
The use of antibiotics has revolutionized treatment and contributed to reducing the need for surgery by half. However, efforts are still needed to develop simple diagnostic tools usable in the field as well as disability prevention methods. The Global Buruli Ulcer Initiative has adopted the strategy recommended by WHO. The strategy is based on early diagnosis of the disease and the use of antibiotics for treatment upon the onset of the first signs by improving access to screening and case management at the most peripheral level of the health system.
more
Environmental Research Volume 151, November 2016, Pages 115-123
Dengue is the world’s most important arboviral disease in terms of number of people affected. Over the past 50 years, incidence increased 30-fold: there were approximately 390 million infections in 2010. Globalization, trade, travel,
...
demographic trends, and warming temperatures are associated with the recent spread of the primary vectors Aedes aegypti and Aedes albopictus and of dengue. Overall, models project that new geographic areas along the fringe of current geographic ranges for Aedes will become environmentally suitable for the mosquito’s lifecycle, and for dengue transmission. Many endemic countries where dengue is likely to spread further have underdeveloped health systems, increasing the substantial challenges of disease prevention and control. Control focuses on management of Aedes, although these efforts have typically had limited effectiveness in preventing outbreaks. New prevention and control efforts are needed to counter the potential consequences of climate change on the geographic range and incidence of dengue, including novel methods of vector control and dengue vaccines.
more
The Marburg Virus Disease (MVD) Response Plan outlines Tanzania’s national strategy for responding to a Marburg virus outbreak declared in the Kagera Region in January 2025. The document describes the current epidemiological situation, assesses the risks posed by the outbreak,
...
and sets strategic objectives to contain the disease and prevent further transmission. It details response measures across multiple sectors, including surveillance, laboratory testing, case management, infection prevention and control, risk communication, logistics, and community engagement. Furthermore, the plan defines coordination mechanisms, operational procedures, monitoring indicators, and the financial resources required to implement the response. Overall, the plan serves as a comprehensive framework to guide national and international stakeholders in controlling the outbreak and protecting public health.
more
The Cholera Q&A Fact Sheet provides essential information about cholera, including its causes, symptoms, treatment, and prevention. Cholera is an acute diarrheal disease caused by Vibrio cholerae, w
...
hich spreads through contaminated water and food. It leads to rapid dehydration and can be fatal if untreated. Symptoms range from mild diarrhea to severe dehydration, shock, and death.
Treatment primarily involves Oral Rehydration Therapy (ORT) to replace lost fluids, and in severe cases, intravenous fluids. Antibiotics are generally not recommended for mass treatment. Prevention focuses on safe drinking water, sanitation, hand hygiene, and proper food handling.
The document also discusses cholera vaccination, with three WHO-approved oral vaccines available. However, vaccines should be used alongside other control measures. The Global Task Force on Cholera Control (GTFCC) aims to eliminate cholera transmission in 20 countries by 2030 through improved sanitation, vaccination, and rapid outbreak response.
more
Every year, millions of patients are affected by infections transmitted during their stay in a health-care facility, where resistant germs are often transferred via the hands of health workers. Resistance to antimicrobials reduces or impedes the effectiveness of any treatment for the
...
prevention and cure of infections. Hand hygiene is the most effective intervention to reduce transmission of infections and resistant germs. The World Health Organization recommends the 5 Moments for Hand Hygiene. Watch this video produced by WHO's Regional Office for the Eastern Mediterranean to learn more about Hand Hygiene and the WHO 5 moments !
more
I examine the effectiveness of donors in targeting the highest burden of malaria in the Democratic Republic of Congo when health information structure is fragmented. I exploit local variations in the burden of malaria induced by mining activities as well as financial
...
and epidemiological data from health facilities to estimate how local aid is matching local health needs. Using a regression discontinuity design, I find significant but quantitatively small variations in aid to health facilities located within mining areas. Comparing local aid with the additional cost of treatment and prevention associated with the increased risk of malaria transmission, I find suggestive evidence that local populations with the highest burden of the disease receive a proportionately lower share of aid compared to neighbouring areas with reduced exposure to malaria infection. The evidence of disparities in the allocation of aid for malaria supports the view that donors may have inaccurate information about local population needs.
more
The Global Health Network is an open source platform that provides trusted knowledge, guidance, tools and resources to support the generation of more and better health research data. During emerging
...
outbreaks it is vital to learn as much as possible to generate evidence on best practice for prevention, diagnosis and treatment and to facilitate effective preparedness and response for future outbreaks.
This pop-up space for 2019 Novel Coronavirus COVID-19 (formerly 2019-nCoV) supports evidence generation by pooling protocols, tools, guidance, templates, and research standards generated by researchers and networks working on the response to this outbreak. Findings from previous outbreaks, largely obtained during MERS and SARS, are also available. This all aims to make research faster and easier and to enable standardised, quality data to be collected and prepared for sharing.
Latest updates will be provided on transmission as well as recommendations for healthcare professionals on transmission, disease management, and care.
more
Tuberculosis in Brazil: the impact of the COVID-19 pandemic
Fernandes Maia, C.M.; Barbosa Martelli, D. R.; Mendes L. da Silveira, D. M.; et al.
Sociedade Brasileira de Pneumologia e Tisiologia
(2022)
CC
J Bras Pneumol. 2022;48(2):e20220082
The spread of Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) continues to progress, causing damage in several countries of the world due to its rapid transmissibility and significant mortality ra
...
tes, despite government measures to contain its transmission, such as movement control, the closing of schools, bans on travel and public gatherings, the mandatory use
of masks, and hand hygiene. The coronavirus disease (COVID-19) has clinical manifestations that are similar to those found in other infections also transmitted through the airways, such as pulmonary tuberculosis (TB) Although TB is a global health problem, it is a curable disease, with affordable treatment and prevention. Nonetheless, it remains one of the leading
causes of death from a single infectious agent worldwide, a situation threatened by COVID-19.
more
Key facts
Buruli ulcer is a chronic debilitating disease caused by an environmental Mycobacterium ulcerans.
At least 33 countries with tropical, subtropical and temperate climates have reported Buruli ulcer in Africa, South America
...
and Western Pacific regions.
It often affects the skin and sometimes bone and can lead to permanent disfigurement and long-term disability.
The mode of transmission is not known and there is no prevention for the disease.
more
