the aid library

A randomized trial of ‘fresh start’ text messaging to improve return to care in people with HIV who missed appointments in South Africa

Njuguna C., L. Long, P. Mistri, et al. Wolters Kluwer Health (2024) C2

AIDS 2024, 38:1579–1588. Treatment interruptions are a barrier to successful antiretroviral therapy (ART). 'Fresh start messages', which leverage significant days on the calendar (e.g., new year, public holiday) in order to prompt action, have the potential to encourage people with HIV (PWH) to re ... more

An open label, block randomized, community study of the safety and efficacy of coadministered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic fila

JambulingamI P. , KuttiattI V.S., Krishnamoorthy K. et al (2021) C2

Better drug regimens for mass drug administration (MDA) could accelerate the Global Programme to Eliminate Lymphatic Filariasis (LF). This community study was designed to compare the safety and efficacy of MDA with IDA (ivermectin, diethylcarbamazine and albendazole) or DA (diethylcarbamazine and ... more

Involving male partners in maternity care in Burkina Faso: a randomized controlled trial

Daniele M.A., Ganaba R., Sarrassat S. et. al. Research (2018) C2

Bull World Health Organ 2018;96:450–461 | doi: http://dx.doi.org/10.2471/BLT.17.206466 The aim of our study was to determine whether an intervention designed to involve the male partners of pregnant women in Burkina Faso in facility-based maternity care influences care-seeking and healthy practi ... more

mHealth intervention “ImTeCHO” to improve delivery of maternal, neonatal, and child care services—A cluster-randomized trial in tribal areas of Gujarat, India

Modi, D., N. Dholakia, R. Gopalan, et al. (2019) CC

Long-acting injectable vs oral antipsychotics for relapse prevention in schizophrenia: a meta-analysis of randomized trials

Kishimoto T., Robenzadeh A, Leucht C, et al. (2014) CC

Schizophr Bull. 2014 Jan;40(1):192-213. doi: 10.1093/schbul/sbs150. Epub 2012 Dec 17.

BCG vaccination induces HIV target cell activation in HIV-exposed infants in a randomized trial

M. A. Gasper, A. C. Hesseling, I. Mohar, et al. JCI insight (2017) C2

Clinical Medicine JCI Insight. 2017;2(7):e91963.

Home visits versus fixed-site care by community health workers and child survival: a cluster-randomized trial, Mali

World Health Organisation (WHO) (2024) C_WHO

Despite recent global declines, under-five mortality remains high in many of the poorest countries. Barriers to timely quality care, including user fees, distance to facilities and the availability of trained health workers and medical supplies, hinder progress in further reducing morbidity and m ... more

Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, PLOS Neclected Tropical Diseases (2016) CC

This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in An ... more

Impact of a Family Clinic Day intervention on paediatric and adolescent appointment adherence and retention in antiretroviral therapy: A cluster randomized controlled trial in Uganda

J. C. Graves; Peter Elyanu; C. J. Schellack; et al. PLOS One (2018) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0192068 March 9, 2018

Assessing the feasibility of interrupting the transmission of soil-transmitted helminths through mass drug administration: The DeWorm3 cluster randomized trial protocol

Ásbjörnsdóttir K.H., Ajjampur S.S.R., Anderson R.M. et al (2018) C2

Soil-transmitted helminths (STH) affect 1.45 billion people worldwide, and high intensity infections are associated with anemia, undernutrition and impaired cognition, particularly among children. Mathematical models suggest it may be possible to interrupt the transmission of STH in a community by e ... more

Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta- Analysis of Randomized Trials

H. T. Ayele, M. S. M. van Mourik, T. P. A. Debray, et al. PLOS One (2015) CC

PLOS ONE | DOI:10.1371/journal.pone.0142290 November 9, 2015; 1 / 16

iSupport, an online training and support program for caregivers of people with dementia: study protocol for a randomized controlled trial in India

Mehta, M.K.; et al. (2018) CC

Trials (2018) 19:271 https://doi.org/10.1186/s13063-018-2604-9 Based on the findings of this trial, we will examine the potential use and scale up of iSupport for caregiver distress in India. This style of online self-help programs could be expanded to other regions or countries or to other suitabl ... more

Early versus late BCG vaccination in HIV-1- exposed infants in Uganda: study protocol for a randomized controlled trial

V. Nankabirwa , J. K. Tumwine, O. Namugga, et al. Trials; BooMed Central (2017) CC

Trials (2017) 18:152, DOI 10.1186/s13063-017-1881-z

Mobile Tuberculosis Treatment Support Tools to Increase Treatment Success in Patients with Tuberculosis in Argentina: Protocol for a Randomized Controlled Trial

Iribarren, S.; Milligan H., Goodwin K., et al. (2021) CC

Anti-interleukin-6 therapies for hospitalized patients with COVID-19: a protocol for a prospective meta-analysis of randomized trials

World Health Organization WHO (2021) C_WHO

19 February 2021 The overall objective of this prospective meta-analyses (PMA) is to estimate the effect of anti-IL-6 therapy compared with usual care in hospitalized patients with suspected or confirmed COVID-19. The primary comparison is of the class effect of anti-IL-6 therapies. It will also es ... more

EFFECTIVENESS OF SHORTENED COURSE (≤ 3 DAYS) OF ANTIBIOTICS FOR TREATMENT OF ACUTE OTITIS MEDIA IN CHILDREN

Gulani, A. & Sachdev, H.P.S World Health Organisation (WHO) (2009) C_WHO

A systematic review of randomized controlled efficacy trials | REPORT - DEPARTMENT OF CHILD AND ADOLESCENT HEALTH AND DEVELOPMENT

Cross-sectional Survey to Assess Prevalence of Disability and Access to Services in Albay Province, The Philippines

Hodge, M., Bolinas, A., Jaucian, E., et al. Disability, CBR & Inclusive Development Journal (DCIDJ) (2017) CC

In this article a cluster randomized cross-sectional survey, conducted in Albay Province in the Philippines in April 2016, was used to assess the prevalence of disability and access to support services. This was done with the purpose of generating ... more

Statement on the use of Dexamethasone for severely ill COVID-19 Patients

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

Africa Centers for Disease Control and Prevention (Africa CDC) is aware of the media releases of the preliminary results of a large randomized clinical trial conducted in the United Kingdom, which included dexamethasone, a corticosteroid, as one of ... more