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Background
The core clinical symptoms of addiction include an enhanced incentive for drug taking (craving), impaired self-control (impulsivity and compulsivity), emotional dysregulation (negative mood) and increased stress reactivity. Symptoms rela
...
ted to impaired self-control involve reduced activity in anterior cingulate cortex (ACC), adjacent prefrontal cortex (mPFC) and other brain areas. Behavioral training such as mindfulness meditation can increase the function of control networks including those leading to improved emotion regulation and thus may be a promising approach for the treatment of addiction.
Methods
In a series of randomized controlled trials (RCTs), we tested whether increased ACC/mPFC activity is related to better self-control abilities in executive functions, emotion regulation and stress response in healthy and addicted populations. After a brief mindfulness training (Integrative Body-Mind Training, IBMT), we used the Positive and Negative Affect Schedule (PANAS) and Profile of Mood States (POMS) to measure emotion regulation, salivary cortisol for the stress response and fMRI for brain functional and DTI structural changes. Relaxation training was used to serve as an active control.
Results
In both smokers and nonsmokers, improved self-control abilities in emotion regulation and stress reduction were found after training and these changes were related to increased ACC/mPFC activity following training. Compared with nonsmokers, smokers showed reduced ACC/mPFC activity in the self-control network before training, and these deficits were ameliorated after training.
Conclusions
These results indicate that promoting emotion regulation and improving ACC/mPFC brain activity can help for addiction prevention and treatment.
more
Drug Facts - Methamphetamine
National Institute on Drug Abuse
(2018)
C2
The webpage by the National Institute on Drug Abuse (NIDA) discusses strategies for preventing drug misuse and addiction. It highlights the importa
...
nce of early intervention, education, and support systems to reduce risk factors and strengthen protective factors. The content emphasizes the role of families, schools, and communities in promoting healthy behaviors and minimizing the likelihood of substance abuse, offering evidence-based prevention programs and practical tips.
more
The Federal Centre for Health Education (BZgA) emphasizes the critical role of drug prevention in enhancing public health in Germany. Annually, the country faces significant premature mortality due to substance use: at least 110,000 deaths from smok
...
ing, 40,000 from harmful alcohol consumption, and approximately 1,300 from illicit drug abuse.
more
La metanfetamina altera las estructuras cerebrales y perjudica la flexibilidad mental
National Institute on Drug Abuse
(2018)
C2
Página actualizada en agosto del 2018: 8/14/18
20 de marzo del 2014
Other Drugs People Use and Misuse
National Institute on Drug Abuse; Easy to read Drug Facts
(2018)
C2
Easy to read Drug Facts
Other Drugs Facts • August 2018 • 1
Treating Opioid Addiction in Criminal Justice Settings
National Institute on Drug Abuse
(2017)
C2
Medication in Prison Associated with Reductions in Fatal Opioid Overdoses After Release
National Institute on Drug Abuse
(2018)
C2
Science Spotlight
February 14, 2018
Commonly abused drugs and withdrawal symptoms
National Institute on Drug Abuse
(2019)
C2
Accessed: 22.03.2019
Principles of Adolescent Substance Use Disorder Treatment: A Research-Based Guide
National Institute on Drug Abuse
(2014)
C2
Substance abuse, is a dangerous relapsing brain disease requiring intensive treatment in a professional setting. Someone who is suffering from substance abuse will have cravings and compulsive
...
drug use that persists even in the face of negative consequences. Although substance abuse may start out as voluntary, over time, the drug changes the way the brain works, leading to tolerance and addiction.
This site is focused on creating clear, accessible, and trustworthy content on substance abuse
more
An Act to repeal the Dangerous Medicines Act of 1973,to ensure the availability of certain drugs for exclusive medical, scientific and related purposes, while preventing their abuse; to prevent the diversion from lawful trade of controlled chemicals
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, controlled equipment and controlled materials for use in the unlawful manufacture of such drugs; to render drug trafficking and related conduct as serious criminal offences and to ensure that trafficking and related conducted as serious criminal offences and to ensure that offenders or suspects are brought to justice; to render certain conduct by drug users as criminal offences, to provide for the treatment and rehabilitation of drug abusing or dependent offenders; to establish the Lesotho Narcotics Bureau; and for related matters.
more
These policy guidelines provide a strategic approach and new recommendations for integrated TB and HIV services for patients suffering from substance-abuse addiction. The key recommendations fall under three main categories: joint planning, key inte
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rventions, and overcoming barriers.
more
Project Bridge: Differentiation of HIV Services for PWID in Harm Reduction Programs in Kazakhstan
Columbia Social Intervention Group; BRIGE; Consortium of Universities for Global Health; National Institute on Drug Abuse
(2019)
C2
Nabila El-Bassel, PhD Columbia University
@NabilaElBassel #CUGH2018
Accessed: 26.09.2019
The pamphlet "Oxycodone" provides an overview of the opioid drug class, explaining its uses, effects, and risks. It describes positive effects like euphoria and pain relief, alongside negative effects such as respiratory depression, confusion, and c
...
onstipation. Withdrawal symptoms include anxiety, increased pain sensitivity, and diarrhea. Treatment options include antagonist therapy (e.g., Naloxone) and substitution therapy (e.g., Methadone or Buprenorphine). The pamphlet emphasizes the importance of emergency care in cases of overdose and encourages seeking professional help for addiction or abuse.
more
Protocol for the management of specialized centres for the treatment of people with alcohol and other drug abuse problems (CETAD) in the framework of the COVID-19 pandemic. Version 1.
The Global status report on alcohol and health and treatment of substance use disorders presents a comprehensive overview of alcohol consumption, alcohol-related harm and policy responses as well as treatment capacities for alcohol and drug use diso
...
rders worldwide. The report is based on data collected by WHO from Member States and organized in accordance with the Sustainable Development Goals health target 3.5 which calls on countries to strengthen “the prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol”. The chapter on alcohol and health continues the series of WHO global status reports on alcohol and health and presents the latest available data on the status of, and trends in, alcohol consumption, as well as estimates of the alcohol-attributable disease burden and descriptions of policy responses worldwide. On the basis of data collected from countries on the treatment of substance use disorders the report describes the status of key components of treatment responses to alcohol and drug use disorders and proposes a new service capacity index for these disorders as an additional contextual indicator for monitoring progress in this domain of SDG health target 3.5. The report concludes with broad directions for international action to accelerate progress towards achievement of SDG health target 3.5.
more
The most frequent health problems of newly arrived refugees and migrants include accidental injuries, hypothermia, burns, gastrointestinal illnesses, cardiovascular events, pregnancy- and delivery-related complications, diabetes and hypertension. Female refugees and migrants frequently face specific
...
challenges, particularly in maternal, newborn and child health, sexual and reproductive health, and violence. The exposure of refugees and migrants to the risks associated with population movements – psychosocial disorders, reproductive health problems, higher newborn mortality, drug abuse, nutrition disorders, alcoholism and exposure to violence – increase their vulnerability to noncommunicable diseases (NCDs)
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