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Buruli ulcer is caused by Mycobacterium and belongs to the family of bacteria that causes tuberculosis and leprosy. Although the causative organism of Buruli ulcer is an environmental bacterium, the mode of transmission to humans remains unknown. The organism produces a unique toxin – mycolactone ... more
Data available for your search include drug targets, tested compounds, existing drugs, ethnopharmacological plants, and information on the genome of M. ulcerans
Poster. Accessed March 11, 2025
Explore a world of health data
Buruli ulcer (BU) is a skin-related neglected tropical disease (skin NTD) caused by infection with Mycobacterium ulcerans. BU is the third most common mycobacterial disease after tuberculosis and leprosy in people who are not immunocompromised. The infection manifests in non-ulcerative forms as no ... more
Pharmaceuticals 2024, 17(6), 691; https://doi.org/10.3390/ph17060691
Although Buruli ulcer, tuberculosis, and leprosy are the three most common mycobacterial diseases, One Health dimensions of these infections remain poorly understood. This narrative review aims at exploring the scientific literature with respect to the presence of animal reservoir(s) and other envir ... more

Clnical and microbiological predictors of healing in Buruli ulcer disease

Agbavor B.; Agbanyo A.; Loglo A. et al. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases (2024) C2
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their use as predictors of time to healing.

Clinical and microbiological predictors of healing in Buruli ulcer disease

Agbavor B.; Agbanyo A.; Loglo A. et al. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases (2024) C2
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their use as predictors of time to healing.
n October 2019, WHO convened the first meeting of the Buruli ulcer laboratory network (BU-LABNET) in Yaoundé, Cameroon, bringing together 11 laboratories from nine countries at the Pasteur Centre of Cameroon (CPC), the network’s Coordinating Centre. The network was formally established at th ... more
Poster
PLoS Negl Trop Dis 16(11): e0010908. https://doi.org/10.1371/journal.pntd.0010908
The aim of the meeting was to broaden the network’s initiatives. Preliminary work involved integrating laboratory testing for skin NTDs other than Buruli ulcer, such as cutaneous leishmaniasis, mycetoma, leprosy and yaws, while extending the network’s reach to encompass additional laboratories.
In the 126 years since it was first described, scientists have learned a great deal about Buruli ulcer, (an ulcerating skin infection caused by the environmental bacterium, Mycobacterium ulcerans), including how to treat it. Yet, there is 1 question about this neglected tropical disease that has rem ... more
Buruli ulcer (BU), a neglected tropical disease (NTD), is an infection of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. The disease has been documented in many South American, Asian, and Western Pacific countries and is widespread throughout much of Africa, especially in West ... more
Status of endemicity of Buruli ulcer 2023
In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagnostic tools usable in the field as well as disabilit ... more
The Lancet Volume 399, Issue 10327p786-797February 26, 2022 Free download after free registration
Journal of Computational Biophysics and ChemistryVol. 22, No. 01, pp. 31-41 (2023)
Countries where buruli ulcer is endemic