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Ebola Synthesis Reference Document

Powell, Steve and others International Federation of Red Cross and Red Crescent Societies (IFRC) (2017) C1

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Report of the Guideline Development Group Meeting on the use of bedaquiline in the treatment of multidrug-resistant tuberculosis

World Health Organization (2017) C_WHO

A review of available evidence (2016). 28-29 June 2016; Geneva, Switzerland The END TB strategy.

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WHO/UNAIDS Annual Meeting with pharmaceutic companies and stakeholders

D. K. Mubangizi; M. Stahl; M. Smid; et al. World Health Organization (2016) C_WHO

Session V: Regulatory & quality assurance aspects Update on prequalification of ARVs and regional harmonisation of medicine registration Deusdedit K. Mubangizi Group Lead, Inspections, WHO-PQT E-mail: mubangizid@who.int Acknowledgements: • Matthias Stahl • Milan Smid • Antony Fake ... more

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Tobacco product regulation

World Health Organization; Together lets beat Tobacco (2018) C_WHO

Building laboratory testing capacity

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The use of bedaquiline in the treatment of multidrug-resistant tuberculosis

WHO (2013) C_WHO

Interim policy guidance

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Impact of the West African Ebola Virus Disease Outbreak on Food security

European Commission Joint Research Centre (2014)

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ADVOCACY TOOLKIT FOR DISABILITY MAINSTREAMING

Africa Disability Alliance (ADA) (2015) C2

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Global spending on health: Emerging from the pandemic

World Health Organization (WHO) (2024) CC

The Global Health Expenditure Report delves into the intricate landscape of global economies and health systems. This year, it focuses on health spending in 2022, the third year of the COVID-19 pandemic. It shows how countries around the world responded to the health and economic shocks of the pande... more

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Towards universal health coverage in the WHO African Region: tracking financial protection

World Health Organization (WHO) (2024) CC

The role of evidence in the journey towards universal health coverage is paramount. Financial risk protection monitoring, the major focus of this report, informs where the WHO African Region stands in reducing the financial hardship people face due to health expenses. This report details the status ... more

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Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ...is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more

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Factors associated with the unsuccessful TB treatment outcomes in the northern regions of Namibia: a mixed methods study

Amkongo, M.; Mitonga, H. K.; Alfeus, A.; et al. (2023) CC2

BMC Infectious Diseases volume 23, Article number: 342 (2023). Tuberculosis (TB) is among the leading causes of death globally. The disease has a huge burden in Namibia, with a case notification rate of at least 442 per 100,000. To date, Namibia is among the countries with the highest global TB bur... more

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Safety of artemisinin and non-artemisinin antimalarials in the first trimester of pregnancy

World Health Organisation (WHO) (2024) C_WHO

Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P... more

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Promoting Quality Malaria Medicines through Social and Behavior Change Communication: An Implementation Kit

Health Communication Capacity Collaborative HC3; USAID (2016) C1

This Implementation Kit (I-Kit), developed by the Health Communication Capacity Collaborative (HC3), helps national and local stakeholders to design country-specific social and behavioural change communication (SBCC) campaigns that address the threat posed by substandard, spurious, falsified and fal... more

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Malaria surveillance, monitoring & evaluation: a reference manual

World Health Organization WHO (2018) C_WHO

Pillar 3 of the Global technical strategy for malaria 2016–2030 calls for the transformation of malaria surveillance into a core intervention in all malaria-endemic countries, as well as in countries which have eliminated malaria but remain susceptible to re-establishment of transmission. This ref... more

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A survey of users on the WHO insecticide susceptibility tube test kit

World Health Organization WHO (2024) C_WHO

The WHO susceptibility test kit has been extensively used for monitoring of insecticide resistance in disease vectors for many years. Over the years, users have reported issues with these kits and potential improvements to WHO in an ad-hoc manner. To systematically determine whether the reported iss... more

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Children face unique vulnerabilities to environmental hazards at every stage of life

UNICEF (2025) C_UNICEF

Fragile Beginnings. The Fragile Beginnings series examines the growing body of research on the unique vulnerabilities of children: in utero and at birth, during infancy and childhood and throughout adolescence. Its purpose is to enable evidence-based advocacy and action on children’s environmental... more

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Climate-proofing a malaria eradication strategy

Nissan, H.; I. Ukawuba, and M. Thomson BMC (2021) CC

Malaria Journal (2021) 20:190

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Framework for Artemisinin resistance prevention, containment, and elimination in South America

Pan American Health Organization PAHO; World Health Organization WHO; instituional Repository for Information Sharing iris (2016) C_WHO

The framework recommends expanded coverage of malaria diagnostic and treatment services, intensified vector control to drive down transmission, strengthened malaria surveillance, and increased transborder collaboration, especially in terms of efforts to control the sale and use of artemisinin monoth... more

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The Malaria Dividend; Why investing in Malaria Elimination creates returns for all

Malaria no more UK; RBM Partnership to End Malaria and Oxford Economics Africa (2024) CC2

Getting back on track to cutting malaria by 90% could boost African economies by $127bn by 2030. This important new report shows we can save lives, boost economies and trade, creating a healthier world

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SuperBetter Children for Health

Children for Health (2022) C1

SuperBetter Children is a health and wellbeing curriculum designed to be integrated into school programmes or offered as an extracurricular activity.