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Diagnosis and Treatment Outcomes of Tuberculosis in Relation to Gender and HIV Status in South Benin

Ablo Prudence Wachinou, Serge Ade, Gildas Agodokpessi, Berenice Awanou, Dissou Affolabi, Wilfried Bekou, Marius Esse, Gabriel Ade, Severin Anagonou, Anthony D. Harries,1Programme National contre la Tuberculose (PNT), Cotonou, Bénin, Eds.: Journal of Tuberculosis Research , (2017)

Journal of Tuberculosis Research, 2017, 5, 189-200 Background: In Benin, little is known about the influence of both gender and HIV-status on diagnostic patterns and treatment outcomes of Tuberculosis (TB) patients. Objective: To assess whether differences in gender and HIV status affect diagnostic patterns and treatment outcomes of TB patients. Methods: Retrospective cohort study of patients registered in 2013 and 2014 in the three largest TB Basic Management Units in south Benin. Results: Of 2694 registered TB patients, 1700 (63.1%) were male. Case notification rates were higher in males compared with females (96 vs 53/100,000 inhabitants). The male to female ratio was 1:1 in HIV positive patients, but was 2:1 among HIV negative cases. In HIV-positive patients, there were no differences in TB types between men and women. In HIV-negative patients, there were significantly higher proportions of females with clinically diagnosed pulmonary TB (p = 0.04) and extrapulmonary TB (p < 0.001). Retreatment TB was 4.65 times higher amongst males compared with females. For New bacteriologically confirmed pulmonary TB, no differences were observed in treatment outcomes between genders in the HIV positive group; but significantly more unfavorable outcomes were reported among HIV negative males, with higher rates of failure (p < 0.001) and loss-to-follow up (p = 0.02). Conclusion: The study has shown that overall TB notification rates were higher in males than in females in south Benin, with more females co-infected with HIV. Unfavorable outcomes were more common in HIV-negative males.

Current Profile of New HIV Infections Among Adults in Northern Benin in 2016

Cossi Angelo Attinsounon, Comlan Albert Dovonou, René Kèkè, Cossi Adébayo Alassani, Kouessi Anthelme Agbodandé, Finagnon Armand Wanvoegbe, Angèle Kouanou-Azon, Djimon Marcel Zannou, Eds.: Science Publishing Group, (2017)

Objective: The study aimed to describe the current epidemiological, clinical and immunological profile of newly detected HIV - positive patients in Northern Benin by 2016. Methods: It was a prospective study conducted from May 2 to October 31, 2016 on three main sites of care of people living with HIV (PLHIV) in the department of Borgou in Benin. All new cases of HIV infection have been systematically and comprehensively recruited. Initial epidemiological, clinical and immunological data were collected using a questionnaire. These data were entered and analyzed using the Epi Info 7 software. Results: In total, 185 adults (68 male and 117 female) newly screened HIV positive were included in this study. The middle age was 36.2 ± 10.9 years and the sex ratio was 0.6 One hundred and thirty-five patients (73%) were between 25 and 50 years old. In terms of the profession, 132 patients (71.3%) were engaged in liberal activities (craftmen, traders and retailers). The majority was schooled (113 or 61.1%) and resided in urban areas (146 or 79%). One hundred and sixteen patients lived in couple (62.7%) with an average monthly income estimated at 70 US Dollars. Clinically, 123 patients (66.5%) were in WHO stage III. The body mass index was over 18.5 kg/m2 in 124 patients (67%). The median number of TCD4 lymphocytes was 254.5 cells/ml and 25 patients (13.5%) had a number of CD4 over 500 cells/ml. HIV1 was really predominant (97.8%). Most patients (152 or 82.2%) had been screened for clinical suspicion. Conclusion: HIV infection in Benin remains the prerogative of young, female, educated and poor people. Screening is delayed and hence the need to develop innovative strategies for early

Follow-up and tracing of tuberculosis patients who fail to attend their scheduled appointments in Cotonou, Benin: a retrospective cohort study

Serge Ade1, Arnaud Trébucq, Anthony D. Harries, Gabriel Ade, Gildas Agodokpessi, Prudence Wachinou, Dissou Affolabi, Sévérin Anagonou, Eds.: BMC Health Services Research , (2016)

Ade et al. BMC Health Services Research (2016) 16:5 Background: In the “Centre National Hospitalier de Pneumo-Phtisiologie” of Cotonou, Benin, little is known about the characteristics of patients who have not attended their scheduled appointment, the results of tracing and the possible benefits on improving treatment outcomes. This study aimed to determine the contribution of tracing activities for those who missed scheduled appointments towards a successful treatment outcome. Methods: A retrospective cohort study was carried out among all smear-positive pulmonary tuberculosis patients treated between January and September 2013. Data on demographic and diagnostic characteristics and treatment outcomes were accessed from tuberculosis registers and treatment cards. Information on those who missed their scheduled appointments was collected from the tracing tuberculosis register. A univariate analysis was performed to explore factors associated with missing a scheduled appointment

Evaluation involvement of local HIV/AIDS nongovernmental organisations in Benin

Maurice T. Agonnoude, François Champagne, Nicole Leduc, Eds.: African Evaluation Journal, (2016)

African Evaluation Journal ISSN: (Online) 2306-5133, (Print) 2310-4988 Background: For some years, non-governmental organisations (NGOs) and civil society have become increasingly involved in the fight against the HIV/AIDS pandemic in Africa. But even though their role is well appreciated, their actions are perceived as ineffective because of a lack of monitoring and evaluation capacity. Objective: This paper aims to describe local HIV/AIDS NGOs’ involvement in evaluation and the characteristics of this involvement.

Characteristics and Treatment Outcomes of Retreatment Tuberculosis Patients in Benin

Serge Ade, Omer Adjibodé, Prudence Wachinou, Narcisse Toundoh, Bérénice Awanou, Gildas Agodokpessi, Dissou Affolabi, Gabriel Adè, Anthony D. Harries, Séverin Anagonou, Eds.: Hindawi , (2016)

Patients with retreatment tuberculosis (TB) represent those who have been treated previously for onemonth ormorewith anti-TB drugs and who have been diagnosed once again with the disease.These patientsmainly include relapses, treatment after failure, or loss to follow-up on a first-line treatment regimen [1]. The number of these patients is not negligible. In 2014, of the 6.3 million TB cases that were notified by National TB Programmes (NTPs) to the World Health Organization (WHO), approximately 700,000 patients were already previously treated

Infection à VIH/SIDA chez les jeunes de 15-24 ans en milieu scolaire au Bénin: le cas de la ville de Cotonou

Saturnine Michozounnou, Moukaïla Amadou (Centre de Formation et de Recherche en matière de Population (CEFORP) , (2011)

Le VIH/SIDA apparaît aujourd’hui comme l’une des pandémies les plus meurtrières au plan mondial. Il touche particulièrement la zone subsaharienne de l’Afrique qui n’abrite guère plus de 10% de la population mondiale mais qui possède près de deux tiers du total des personnes infectées par le VIH. Au Bénin la prévalence du VIH s’était stabilisée autour de 2% de 2002 à 2005 avant de passer en 2006 à 1,2% selon l’EDSB III. Cette prévalence faible présente des disparités régionales et sociales. Les tendances épidémiologiques récentes révèlent que l’affection du VIH/SIDA touche une population de plus en plus jeune et de plus en plus féminine. Mais quelle est la situation des jeunes scolaires de 15-24 ans ? C’est là la principale préoccupation prise en compte par cette communication qui vise à analyser l’influence de l’environnement scolaire sur les risques en termes de sexualité des jeunes de 15-24 ans.

Le fonctionnement de la prise en charge des patients séropositifs au Bénin, le cas de l’Atacora

Perrine Bonvalet, (2006)

Le fonctionnement de la prise en charge des patients séropositifs au Bénin, le cas de l’Atacora

1ère Conférence internationale des ministres de la santé sur la sécurité des patients et la gestion des risques en milieux de soins en Afrique, Rapport Final

CIMSEF, (2012)

1ère Conférence internationale des ministres de la santé sur la sécurité des patients et la gestion des risques en milieux de soins en Afrique, Rapport Final 2012

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