Emergencias 2021: 33: 42-58
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The Essential WASH Actions toolkit expands the connection between WASH and nutrition. This resource offers a comprehensive set of essential WASH actions, references training materials for health workers, nutrition managers and community workers to build capacity, and outlines accompanying behaviors ...needed to support the Essential Nutrition Actions.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Research Article 
PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002625 July 31, 2018 / 1-19
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                This paper focuses on the Sustainable Development Goals related to poverty, economic growth, inequality, health, food production and the environment. It presents concrete examples of the underlying and complex aspects of antibiotic resistance and its impacts across different Sustainable Development ...Goals. The aim of this paper is to inform and stimulate discussions on how to further advance the implementation of 2030 Agenda for Sustainable Development, the Global Action Plan on Antimicrobial Resistance, National Action plans on Antimicrobial Resistance, as well as work within all sectors that affect and are affected by antibiotic resistance
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                La détection directe des protéines virales du SRAS-CoV-2 (antigènes) dans les écouvillons nasaux et autres sécrétions respiratoires à l'aide de tests immunologiques à flux latéral (également appelés tests de diagnostic rapide, TDR) offre une méthode plus rapide et moins coûteuse pour te...ster le SRAS-CoV-2 que la méthode de référence, les tests d'amplification des acides nucléiques (TAAN). Ces lignes directrices provisoires offrent des recommandations sur les utilisations prioritaires des tests de diagnostic rapide à détection d'antigène (TDR-Ag) dans des populations et des contextes spécifiques, notamment (i) pour la détection primaire des cas chez les personnes symptomatiques suspectées d'être infectées et les personnes asymptomatiques à haut risque de COVID-19, (ii) pour la recherche des contacts, (iii) pendant les enquêtes sur les épidémies et (iv) pour surveiller les tendances de l'incidence de la maladie dans les communautés. Les TDR-AG répondant aux exigences minimales de performance peuvent être utilisés en dehors des milieux cliniques et des laboratoires, y compris dans les communautés, par des opérateurs formés conformément aux instructions. Le guide fournit en outre des recommandations sur la mise en œuvre, la sélection des produits et le stockage
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The guidelines are primarily intended for health-care professionals working in first- or second-level health-care facilities, including emergency, inpatient and outpatient services. They are also directed at policy-makers, health-care planners and programme managers, academic institutions, non-gover...nmental and civil society organizations to inform capacity-building, teaching and research agendas.
Web annex A provides the quantitative evidence reports, Web annex B summarizes the qualitative and economic evidence and Web annex C presents the Evidence-to-Decision frameworks.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Diabetes is a significant public health issue that affects approximately one in 10 adults globally, with type 2 diabetes accounting for 90–95% of cases. This chronic condition causes considerable morbidity and mortality and is growing in impact, with cases projected to rise from 537 million in 202...1 to 784 million by 2045. As cases rise, it is imperative to ensure the healthcare workforce is prepared to care for affected individuals. However, there is a growing global shortage of healthcare workers, which was estimated, pre pandemic, to reach 15 million by 2030. Therefore, all of the healthcare workforce will need to be utilised to their fullest potential in order to address the growing global burden of diabetes. Pharmacists will continue to be essential in this endeavour.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Improving the quality of hospital antibiotic use is a major goal of WHO’s global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally.... We aimed to present data on patterns of paediatric AWaRe antibiotic use that could be used for local and national stewardship interventions.
www.thelancet.com/lancetgh Vol 7   July 2019
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The WHO Global Tuberculosis Report 2022 provides a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets.
...
The 2022 edition of the report is as usual, based primarily on data gathered by WHO from national ministries of health in annual rounds of data collection. In 2022, 202 countries and territories with more than 99% of the world’s population and TB cases reported data
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                El  31  de  diciembrede  2019  las  Autoridades  de  la  República  Popular  China,  comunicaron  a  la OMS varios casos de  neumonía de etiología desconocida en Wuhan, una ciudad situada en la provincia  china  de  Hubei.  Una  semana  más  tarde  confirmaron  que  se  trataba  de  un  nuevo co...ronavirus  que  ha  sido  denominado  SARS-CoV-2. Al  igual  que  otros  de  la  familia  de  los coronavirus, este  virus causa  diversas  manifestaciones  clínicas  englobadas bajoel  término COVID-19,  que  incluyen  cuadros  respiratorios  que  varían  desde  el  resfriado  común  hastacuadros  de  neumonía  grave  con  síndrome  de  distrés  respiratorio,  shock  séptico  y  fallo  multi-orgánico. La  mayoría  de  los  casos  de  COVID-19  notificados  hasta  el  momento  debutan  con cuadros leves.Un  punto  de  detección  importante  de  casos de COVID-19es la urgencia  hospitalaria. El triaje tiene   como   objetivo identificar   y priorizar   al   paciente   más   grave. Al   tratarse   deuna enfermedad transmisiblese debenextremar las medidas deprecaución.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The Coronavirus Disease 2019 (COVID-19) has had a continuous and robust impact on world health. The resulting COVID-19 pandemic has had a devastating physical, mental and fiscal impact on the millions of people living with noncommunicable diseases (NCDs), as they have a higher risk of severe illness... and death from COVID-19. COVID-19 has been associated with an
excess in all-cause and cardiovascular disease (CVD) mortality beyond that related to the infection itself and its immediate consequences. Studies in the
United Kingdom (UK) and United States of America (USA) have clearly shown increasing deaths from ischemic heart disease, stroke and hypertensive disease due to COVID-19. Overall, the impact has been greater in individuals with lower socioeconomic status, even in high income nations.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Este manual constituye un esfuerzo por ser una herramienta de primera
mano, que demarca de manera sencilla los lineamientos para la atención
del paciente con diagnóstico de Enfermedad Chagas. Está basado en
evidencias clínicas recientes y recomendación de expertos nacionales e
internacional...es y está adaptado a las condiciones y características
epidemiológicas del país.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The WHO Global tuberculosis report 2024 provides a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets.
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                Each year, the WHO Global TB Report provides a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets.
The... 2021 edition of the report has been produced in a new and more web-centric format. This is designed to make the content available in smaller (more “bite-sized”) chunks that are easier to read, digest, navigate and use. There is a short and slim report PDF with 30 pages of main content plus six short annexes. This is accompanied by expanded and more detailed digital content on web pages. The total amount of content remains similar to that of previous years.
Available in English, French, Arabic and Chinese
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The World Climate and Security Report (WCSR) 2021 from the Expert Group of the International
Military Council on Climate and Security is a global assessment of the security dimensions of a changing
climate and effective means to address them. It is intended to inform timely climate and security po...licy
and action, and builds upon the analysis in the first WCSR, released in February 2020.
                                                                    more
                                                            
                         
                     
                                                        
                        
                        
                            
                            
                                                                The World Climate and Security Report (WCSR) 2021 from the Expert Group of the International Military Council on Climate and Security is a global assessment of the security dimensions of a changing climate and effective means to address them. It is intended to inform timely climate and security poli...cy and action, and builds upon the analysis in the first WCSR, released in February 2020.
                                                                    more