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EPI 1: Antiepileptic medications for management of acute convulsive seizures when no intravenous access is available

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[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?
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Antibiotic stewardship interventions in hospitals in low-and middle-income countries: a systematic review

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Objective: To review the effectiveness of antibiotic stewardship interventions in hospitals in low- and middle-income countries.
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Zika causality statement

World Health Organization WHO (2016) C_WHO
Zika virus infection: update on the evidence for a causal link to congenital brain abnormalities and Guillain-Barré syndrome Update 7 September 2016
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Prevalences of dementia and cognitive impairment among older people in sub-Saharan Africa: a systematic review

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Antidepressants (Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors) in treatment of adults with depression

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Kangaroo mother care: a practical guide
recommended

World Health Organization WHO (2003) CC
Kangaroo mother care is a method of care of preterm infants. The method involves infants being carried, usually by the mother, with skin-to-skin contact. This guide is intended for health professionals responsible for the care of low-birth-weight and preterm infants. Designed to be adapted to local ... more
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Vector control interventions designed to control malaria in complex humanitarian emergencies and in response to natural disasters

World Health Organization WHO (2021) C_WHO
“Preferred product characteristics” (PPCs) are key tools to incentivize and guide the development of urgently needed health products. Some of the vector control interventions deployed in complex emergencies and in response to natural disasters – namely insecticide-treated nets (ITNs) and indoo... more
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Evaluation of COVID-19 vaccine effectiveness in a changing landscape of COVID-19 epidemiology and vaccination

World Health Organization WHO (2022) C_WHO
Interim Guidance October 2022. This addendum addresses some of the methodological aspects of VE evaluations that have been learned during the past year, as well as those that have become relevant in the current epidemiological setting of the COVID-19 pandemic. For some of the COVID-19 vaccine method... more
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Treatment of Mycobacterium Ulcerans Disease (Buruli Ulcer)
recommended

World Health Organization WHO WHO (2012) C_WHO
Guidance for health workers
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Physical Activity

World Health Organization WHO (2012) C_WHO
Q6: Is advice on physical activity better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder with inactive lifestyles
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Dual HIV/syphilis rapid diagnostic tests can be used as the first test in antenatal care

World Health Organization WHO (2019) C_WHO
Policy Brief. WHO recommends that pregnant women receive testing for HIV, syphilis and hepatitis B (HBSAg) at least once during pregnancy, preferably in the first trimester. Dual HIV/syphilis rapid diagnostic tests (RDTs) can be used as the first test for pregnant women as part of antenatal care (... more
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The Global Breast Cancer Initiative (GBCI

World Health Organization WHO (2021) C_WHO
The Global Breast Cancer Initiative, established by WHO in 2021, will provide guidance to governments on health systems strengthening for breast cancer. This illustrated summary outlines its goals, rationale and framework.
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Evaluation guidelines for Measles supplemental immunization activities

World Health Organization; Regional Office for Africa (2006)
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Prevention of potential sexual transmission of Zika virus. Interim guidance update
recommended

World Health Organization WHO (2016) C_WHO
Updated 6 September 2016. This guidance has been developed to provide advice on the prevention of potential sexual transmission of Zika virus. The primary transmission route of Zika virus is via the Aedes mosquito. However, sexual transmission of Zika virus may also be possible, with limited evidenc... more
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EFFECTIVENESS OF SHORTENED COURSE (≤ 3 DAYS) OF ANTIBIOTICS FOR TREATMENT OF ACUTE OTITIS MEDIA IN CHILDREN

Gulani, A. & Sachdev, H.P.S World Health Organisation (WHO) (2009) C_WHO
A systematic review of randomized controlled efficacy trials | REPORT - DEPARTMENT OF CHILD AND ADOLESCENT HEALTH AND DEVELOPMENT
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Hypertension and COVID-19 (Arabic Version)

World Health Organization WHO (2021) C_WHO
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Status of Antiretroviral Therapy Service Delivery in Uganda

Ministry of Health, Uganda (2010) C1
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Tuberculosis and Non-Communicable Diseases

World Health Organization; Global TB Programme; Hannah Monica Dias Policy, Strategy and Innovations (2017) C_WHO
END TB Second Meeting of th WHO Global Coordination Mechanism (GCM/NCD) Working Group on the inclusion of NCDs in other programmatic areas. Accessded December 2017