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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Birth defects surveillance: a manual for programme managers

World Health Organization (2014)

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The compound impact of extreme weather events and COVID-19

Walton D., Arrighi J., et al. IFRC - International Federation of Red Cross (2021) C2

From the start of the COVID-19 pandemic until August 2021, extreme weather events have affected at least 139.2 million people and killed at least 17,242 people in at least 433 unique events. These figures are certainly an underestimate, as they do not include estimates of numbers of people affected ... more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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The World Climate and Security Report 2021

Brock, S.; Barrett, O.L.; Birkman, L.; et al. International Military Council on Climate and Security (2021) CC

The World Climate and Security Report (WCSR) 2021 from the Expert Group of the International Military Council on Climate and Security is a global assessment of the security dimensions of a changing climate and effective means to address them. It is intended to inform timely climate and security po... more

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Working with Individuals, Families and Communities to Improve Maternal and Newborn Health. Module 5

World Health Organization WHO; PAHO Pan American Health Organization, Enfant du Monde (2017) C_WHO

A Toolkit for Implementation. Module 5: Finalizing, monitoring and evaluating the IFC action plan

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Shaping the Future: How Changing Demographics Can Power Human Development

Palanivel, T. , et al. United Nations Development Programme (2016) C1

Asia-Pacific Human Development Report

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Guidelines for essential trauma care
recommended

Mock, C et al World Health Organization (WHO) (2004) C_WHO

The Guidelines for essential trauma care seek to set achievable standards for trauma treatment services which could realistically be made available to almost every injured person in the world. They then seek to define the resources that would be necessary to assure such care. These include human res... more

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WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update
recommended

World Health Organization WHO (2021) C_WHO

6 July 2021. The “WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update” is the latest document replacing the one issued in 2020. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included in the... more

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Uso problemático de internet

J. Pei-Chen Chang; C.-C. Hung IACAPAP (2017) C2

Otros desórdenes Capítulo H.6 Editor: Laura Revert Marín, Matías Irarrázaval & Andres Martin Traducción: Silvia Rodriguez Portillo, Alfonso Pastor Romero y Paula Cox

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The West African Initiative for Climate-Smart Agriculture (WAICSA)

Chiriac, D.; et al. GIZ; Bloomberg Philatrhopies, IFAG; et al. (2019) CC

The Lab identifies, develops, and launches sustainable finance instruments that can drive billions to a low-carbon economy. The 2019 Global Lab Cycle targets four specific sectors across mitigation and adaptation: blue carbon in marine & coastal ecosystems; sustainable agriculture for smallholde... more

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Compendium of forgotten foods in Africa: A companion publication for Integrating Africa’s forgotten foods for better nutrition
recommended

Food and Agriculture Organization of the United Nations FAO (2024) CC

The Food and Agriculture Organization of the United Nations has launched a new Compendium of forgotten foods in Africa which is a first-of-its-kind comprehensive collection of 100 African forgotten food crops. Also referred to as neglected, underutilized or orphan crops, these species offer valua... more

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Abortion care guideline

World Health Organization WHO (2022) C_WHO

The objective of this guideline is to present the complete set of all WHO recommendations and best practice statements relating to abortion. While legal, regulatory, policy and service-delivery contexts may vary from country to country, the recommendations and best practices described in this docume... more

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Availability, Affordability, Access, and Pricing of Anti-cancer Medicines in Low- and Middle-Income Countries: A Systematic Review of Literature

Ocran Mattila, P.; R. Ahmad, S.Shahzad Hasan, et al. (2021) C2

Front. Public Health, 30 April 2021 | https://doi.org/10.3389/fpubh.2021.628744

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Essential Nutrition Actions: mainstreaming nutrition throughout the life course

World Health Organization WHO (2019) C_WHO

This publication’s primary purpose is to provide a compilation of actions to address malnutrition in all its forms, in a concise and user-friendly format to help in decision-making processes for integration of nutrition interventions in national health policies, strategies, and plans based on coun... more

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Consolidated Guidelines on HIV Prevention, Diagnosis, Treatment and Care for key populations

C. Beyrer; A. Kamarulzaman; E. Aaraj; et al. World Health Organization WHO (2016) CC

2016 Update Key population

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State of the 2020 World's Nursing - Investing in education, jobs and leadership

World Health Organization WHO (2020) CC

The State of the world’s nursing 2020 report provides the latest, most up-to-date evidence on and policy options for the global nursing workforce.

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TB, HIV, mothers and children: time for action

Theo Smart Aidsmap (2012)

HIV & AIDS Treatment in Practice No. 188

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Migration in Malawi

International Organization for Migration IOM (2015) C2

A country Profile 2014

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Informe mundial sobre la discapacidad

World Health Organization (WHO) & The World Bank (WB) (2011) C_WHO

Guidelines for essential trauma care recommended

WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update recommended

Compendium of forgotten foods in Africa: A companion publication for Integrating Africa’s forgotten foods for better nutrition recommended

Guidelines for essential trauma care
recommended

WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update
recommended

Compendium of forgotten foods in Africa: A companion publication for Integrating Africa’s forgotten foods for better nutrition
recommended